The Computational Biomechanics Lab at Michigan State University is looking to fill fixed-term research associate positions. The successful candidate must have a Ph.D. in either mechanical, biomedical, aeronautical, civil engineering, or equivalent field with a strong foundation in programming (C++ and python), computational mechanics, and the finite element method. Special consideration will be given to candidates who are familiar with the open-source finite element library FEniCS, cardiac finite element modeling, medical image processing, and machine learning. The candidate is expected to possess excellent communication and writing skills. In this position, the candidate will work to develop multiscale/multiphysics formulations and code to solve problems related to the cardiovascular system. Additionally, the selected candidate will be expected to help mentor students and publish peer-reviewed journal articles. The successful candidate will enjoy ample training and network!
Outstanding candidates are invited to submit a letter of application detailing their relevant background, providing the names and e-mail addresses of at least three references, a CV to the webpage: careers.msu.edu/cw/en-us/job/509746/research-associatefixed-term
For more information, please contact Dr. Lik Chuan Lee at lclee@egr.msu.edu
Academic Context: The post-doctoral fellow will join the STBio team, from the Centre Ingénierie et Santé (Mines Saint-Etienne) and the SaInBioSE laboratory (INSERM U1059), whose research activities are focused on soft tissue biomechanics. For several years, STBio has been working on the interactions between medical textile devices and the skin, in order to better understand their mechanisms of action and/or to prevent certain complications.
Background: The device under study is a very innovative system developed for the treatment of lymphedema. It consists of a compressive envelope with a structured inner face. Although several clinical investigations have shown its efficiency, its mechanism of action remains poorly understood. It is based on the interface pressure, but also on its spatial and temporal variation, that is exerted on the surface of the skin. The geometrical structure of the inner face determines these pressure variations.
The Karl Landsteiner University of Health Sciences (KL) is part of an academic and research community located at the Campus Krems, and includes a network of comprising teaching hospitals in St. Pölten, Krems, Tulln and Eggenburg. KL is committed to raising its profile in specific areas of biomedicine, biomedical engineering, and biopsychosocial sciences by entering into strategic academic and research partnerships with other institutions.
From Autumn 2022 the KL offers a 2-year research position at the Division „Biomechanics“ (Head: Univ. Prof. Dr. Dieter Pahr) with the option of getting permanent upon adequate performance: Research Assistant/ Lab Manager (Post Doc) (40 h) (f/m/d). The Division Biomechanics is part of Prof. Pahr’s Interuniversity Biomechanics Laboratory, which also includes his research group at the TU Wien. Get some impressions of our recent work from our Youtube Channel!
Your tasks: • Independent experimental research activities in the field of musculoskeletal biomechanics • Publication activities and writing of applications for external funding • Teaching and support in administrative tasks • Supervision of Bachelor, Master and PhD students • Administration and maintenance of the laboratory infrastructure • Support of the laboratory head
Your Profile: • Completion of a suitable doctorate (e.g. mechanical engineering, physics, biomedical engineering, …) • In-depth knowledge in biomechanical testing (material and/or implant testing incl. programming of measurement data analysis) • Appropriate track record of publications in scientific journals as well as conference contributions. • Experience with clinic-related research and imaging techniques (CT or MRI) would be an advantage • Good German and very good English skills, both written and spoken • Process-oriented, accurate, structured way of working with a strong ability to prioritize • Open, resilient and flexible personality with a professional attitude
Your Perspective: You can expect a challenging job in a highly motivated team. KL is committed to an anti-discriminatory employment policy and values equal opportunities and diversity. KL specifically encourages qualified people with different diversity characteristics (gender, age, ethnicity, denomination, sexual orientation, etc.) to apply. The minimum monthly gross salary for this position is 3,670 € (40 hrs) gross per month. Readiness for overpayment exists with appropriate experience and qualification.
Applications should include a motivation letter, curriculum vitae and credentials and should be mailed to Ms. Christina Schwaiger of the Karl Landsteiner University of Health Sciences, Dr.-Karl-Dorrek-Straße 30, 3500 Krems, Austria (bewerbung@kl.ac.at ) referring to jobnumber “2202”. There is the possibility of an ongoing job application until a suitable candidate is found.
The MAtrix / Mechanobiology & Tissue Engineering research group (www.mech.kuleuven.be/mechanobiology) is a bioengineering group that is pioneering the role of cellular forces for microvascular formation and function in health and disease. The group is led by prof. Hans Van Oosterwyck and is one of the few groups worldwide that has established 3D Traction Force Microscopy (TFM) routines and workflows for quantifying cellular force exertion in 3D, and routinely applies them to in vitro models of angiogenesis (endothelial invasion). Together with its research partners, it is currently developing novel in vitro models, compatible with TFM and other methods of cellular force inference, to study the interplay between cellular force exertion, matrix mechanics and fluid flow, and how this interplay contributes to endothelial cell phenotypic changes in the context of endothelial heterogeneity and specific (genetic) diseases that lead to microvascular malformations. The group is looking for a postdoc with strong expertise in the in vitro bioengineering of microvascular networks to strengthen the research team.
The ideal candidate must have: – a PhD in bioengineering or related fields. – strong bioengineering skills relevant for 3D in vitro models of vascular biology, such as micro- or mesofluidics, micro- / biofabrication (e.g. 3D printing), 3D endothelial (co-) culture systems, hydrogel synthesis and functionalization, mechanical design. – experience with optical microscopy, preferably live cell imaging in 3D (confocal microscopy, fluorescence microscopy, genetically-engineered fluorescent reporter systems). – some experience with or exposure to scientific computing (such as finite element modelling) and programming (such as Matlab). – a strong interest in mechanobiology and mechanotransduction, with a desire to learn TFM and related methods. – a strong CV and willingness to apply for a personal postdoc fellowship (together with the PI). – a collaborative attitude; we are looking for a real team player who is willing to help and co-supervise master and PhD students.
You will join a KU Leuven-funded project that is in close collaboration with profs. Liz Jones and Aernout Luttun (Centre for Molecular and Vascular Biology at KU Leuven) and that explores how organ-specific endothelial cell heterogeneity arises from the combination of genetic and mechanical signals. Your role is to explore the role of cellular force exertion in the establishment of organ-specific endothelial phenotypes in combination with extrinsic mechanical signals related to organ-specific matrix mechanics and fluid flow. Apart from using and optimizing recently established monolayer models available in our group, you are expected to develop novel 3D in vitro models of perfused vascular networks compatible with cellular force inference. Apart from the application to the study of endothelial cell heterogeneity, these models must also target the study of microvascular disease, in particular Cerebral Cavernous Malformations (CCMs) which are malformations of the brain microcapillaries. As to the latter, the Van Oosterwyck group has a strong partnership with the research group of dr. Eva Faurobert at the Institute for Advanced Biosciences (University of Grenoble, France), with whom you are expected to closely collaborate as well.
The research projects about biomechanics cover in silico methodologies, deep learning, experimental and computational characterization of biological tissues and biomaterials, and imaging techniques. Among the research projects advertised, you will find:
– I-BLOSSOM – Instrumented Biomarkers for LOngitudinal aSSessment Of Motor control development (Supervisor: Prof Stagni, rita.stagni@unibo.it)
– Development and perspective validation of an in silico methodology for the prediction of bone fracture risk to be used as clinical support system (Supervisor: Prof. Viceconti, marco.viceconti@unibo.it)
– Biomechanical evaluation of knee mechanical behaviour and interface stresses with a new concept of alignment for total knee arthroplasty (NEW- KNEE) (Supervisor: Prof. Cristofolini, luca.cristofolini@unibo.it)
– Computational modelling of vertebrae affected by metastasis for clinical diagnosis (Supervisor: Prof. Cristofolini, luca.cristofolini@unibo.it)
PhD candidates are expected to operate in a multidisciplinary team of engineers, biomaterials science, medical physics, computer science, biologists and clinicians. Each project will be conjointly supervised by a supervisor active in the technology field and one in the clinical field.
The online application must be submitted by June 9th, 2022 at 11.59 pm (CEST).
Three totally founded PhD scholarships are available.
If you would like to apply, contact the coordinator of the PhD programme (prof. Marco Viceconti, marco.viceconti@unibo.it) or the supervisor of the project you are interested in and join the University of Bologna for a wonderful research experience.
As part of the development of research activities in biomechanics and teaching activities in mechanical engineering, the University of Montpellier is recruiting for a non-permanent position of junior research professor in soft tissue biomechanics. Through here/his project, she/he will increase our knowledge and understanding of poro-elastic fibrous tissues (with a focus on cartilages) and of the contact mechanisms between those tissues in joints. Understanding these behaviors, including fluid-structure mechanisms could lead to (i) better understanding of the mechanobiological behavior and growth of cartilage and (ii) better understanding and modeling of contact mechanisms within joints and thus propose strategies for rehabilitation. Robotic solutions, different imaging modalities (US, MRI, microCT, microsopy,…), biosensors and 3D bioprinting may be developed/used in here/his research project, with the help of collaborative research between labs of the University.
Senior Scientist and head of newly built and equipped human movement lab staff position for a biomechanical engineer with mechanical/mechatronics engineering background and interest in Human Movement Biomechanics and development of assistive devices, available at Vienna University of Technology. The position is initially limited to two years, extension to permanent position possible.
A postdoctoral researcher position is available in the Developmental Biomechanics Group. The research project is focussed on cartilage development and healing, and will be in close collaboration with Prof Pieter Brama from the UCD School of Veterinary Medicine. Experimental (wet lab, e.g., histology) experience (ideally) with musculoskeletal tissues is essential for the position. The funding available is for nine months, but every effort will be made to extend the duration of the position. The start date is asap, and latest July 2022.
The Institute of Lightweight Design and Structural Biomechanics (ILSB) of TU Wien invites applications for the position of a University Assistant (30h/week) in the area of biomechanics and proteomics. The successful candidate will conduct research towards a PhD thesis. In particular he/she will investigate healthy and degenerated meniscal tissue micro- / nano-mechanics using atomic force microscopy, spatially resolved micro-indentation and dedicated existing custom-made devices. Composition will be investigated via spatially mass-spectrometry methods under supervision of Prof. M. Marchetti-Deschmann of the Institute of Chemical Technologies and Analytics of TU Wien. After successfully establishing correlated mechanics and compositional datasets, a further step would be to compare retrieved data, to chemical magnetic resonance images (MRI) available through a clinical partner. In the long run we envision this to become a tool for early detection of meniscal degeneration and osteoarthritis.
Heart failure is a progressive chronic condition under which heart tissues undergo detrimental changes in structure and function across multiple scales in time and space. Given the role that biomechanical stimuli play in the onset and progression of these remodeling processes, cardiac restraint devices are seen as a promising treatment strategy. However, given the limited understanding of the underlying cardiac tissue behavior, current designs fail to successfully counteract pathological remodeling in the long term.
To this end, the aim of this PhD project is to develop, implement, verify, calibrate, and validate a microstructurally and functionally informed cardiac tissue model for growth and remodeling using finite element analysis. The outcomes of the developed framework will be leveraged to design enhanced bio-informed cardiac restraint devices.
Within this project, the PhD candidate is expected to operate within a multidisciplinary team of engineers, biomedical scientists, and cardiac surgeons. The outcomes of this project will be disseminated to the scientific community and to a general audience through presentations at (inter-)national conferences and through publications in peer-reviewed journals. Additionally, the candidate is expected to take part in educational activities within the department (assist in teaching, act as a mentor for master students, supervise master thesis work, … ).
The PhD candidate will be supervised jointly by dr. ir. M. Peirlinck (dept. of Biomechanical Engineering) and dr. ir. Noël (dept. of Precision & Microsystems Engineering) at Delft University of Technology. Our labs have a strong network of national and international collaborators in both academia and industry.
