The Institiute of Medical and Biological Engineering (IMBE) in Leeds, UK, is currently recruiting for 4 positions:
- researcher (research fellow requiring a PhD or research assistant requiring a Master) in computational damage biomechanics: https://jobs.leeds.ac.uk/vacancy.aspx?ref=EPSME1154 (for the research assistant role, check your UK working eligibility by contacting InternationalHR@leeds.ac.uk)
- post-doctoral research (research fellow requiring a PhD) in knee and hip biomechanical evaluation: https://jobs.leeds.ac.uk/vacancy.aspx?ref=EPSME1155
- PhD student in spine biomechanics: https://phd.leeds.ac.uk/project/1826-integrating-morphology-and-mechanics-developing-a-statistical-shape-and-appearance-model-ssam-for-spinal-health-assessment-intervention-planning
- PhD student in bone healing: https://phd.leeds.ac.uk/project/1820-computational-biomechanical-modelling-of-external-fixation-of-fractures-to-predict-bone-healing
All details of application processes are available on the respective links, deadlines within the next month.
The multi-disciplinary IMBE is embedded within the School of Mechanical Engineering and the Faculty of Biological Sciences at the University of Leeds. It is a dynamic world-renowned medical engineering research centre which specialises in research and translation of musculoskeletal and cardiovascular medical technologies that promote ’50 active years after 50’.
As a researcher or PhD student within IMBE, there will be opportunities to contribute to wider activities related to medical technologies including public and patient engagement, group training and social events. Groups of researchers working on aligned projects or using similar methods meet regularly to share ideas and best practice, and we encourage collegiate working. We will support your long-term career ambitions through bespoke training and encourage external secondments, laboratory visits or participation at international conferences.
REBONE is a four-year Doctoral Network, funded by the Europe Horizon Marie Skłodowska programme, aiming at innovatively training a new generation of researchers to develop a multidisciplinary optimization process aimed at providing technologies for personalized bone-substitute implants, based on bioactive ceramics to address the health and societal burdens of trauma and bone diseases.
The musculoskeletal system is extremely vulnerable to ageing and traumatic events, and common clinical conditions often impose a high burden on the clinical system. For patients requiring bone-substitute implants to treat critical-size bone defects, new solutions are needed to address important unmet needs: personalised solutions for better clinical outcomes; improvements in materials to ensure higher mechanical reliability without compromising bioactive and bioresorbable properties; optimised manufacturing technologies for materials and products of high reliability and quality.
In order to achieve these ambitious goals REBONE is about to open 10 fully funded PhD positions to construct a platform of computational tools that will enable clinical experts to produce customized bone graft substitutes for the treatment of critical-size bone defects. This innovation will ensure that an ideal treatment solution is found on a patient-specific basis in terms of:
- mechanical and mechano-biological performance,
- surgical implantability, and
- manufacturing process reliability.
Furthermore, REBONE will develop state-of-the-art in silico models based on advanced computational methods and advanced characterisation and validation techniques to obtain personalised implants with a surgical planning visualization system in mixed reality with the following characteristics:
- tailored and reliable mechanical and physical properties;
- best osteointegration capability;
- targeted mechanical, physical and mechano-biological functions with patient-specific constraints taking into account the load-bearing anatomical location. Four selected clinical cases will be used as demonstrators of the optimization design and manufacturing processes.
LIST OF AVAILABLE PhD POSITIONS
Complete list of the 10 Doctoral positions available within REBONE:
- Position 1: Methods for optimization of bone-substitute architectures (Politecnico di Milano, Italy);
- Position 2: Micro- and macro-mechanical characterization of materials and devices and in-silico Models (Politecnico di Milano, Italy);
- Position 3: 3D printing technologies for Glass-Ceramic and Glass-Ceramic-based composite BTE scaffolds (Politecnico di Torino, Italy);
- Position 4: Tissue-scaffold biological interaction (Università del Piemonte Orientale, Italy)
- Position 5: Design of bone inspired scaffolds and biomechanical characterization of the bone-scaffold construct (Université de Liege, Belgium)
- Position 6: Industrial process for glass-ceramic device manufacturing through VPP (Lithoz GmbH, Austria)
- Position 7: Characterization of fracture relevant bone sites for information on the structural/compositional requirements of the implant (Ludwig Boltzmann Institute, Austria)
- Position 8: Models for Tissue growth and fundamental relationships with micro-architecture of scaffolds (University of Salzburg, Austria)
- Position 9: Biomimetic in vitro culture models for evaluation of novel bone substitute implants (University of Belgrade, RS)
- Position 10: Mixed reality for planning of implant surgery for bone defects of irregular shapes (MEDAPP SPÓŁKA AKCYJNA, Poland)
For info and application procedure please visit the project website https://rebone.eu/ and here:
The objective of this joint project (LBA & LBMC) is to integrate the barrier impact into the airbag evaluation processes of the previous REGAM project. This objective thus feeds two strategic issues:
– Quantify the combined effects of wearing an airbag vest and of a safety barrier with or without a motorcyclist screen to reduce the risk of injury during an accident (definition, analysis and choice of injury criteria in a reference case).
– Identify the area of protection (gain/limits) offered by regulatory barriers for different impact situations with the motorcyclist (sensitivity analyses).
To do this, it is a question of establishing a crash numerical modeling combining motorcyclist, motorcycle, airbag and restraint device, based on the previous work on the subject at LBA and LBMC.
More details can be found here:
The Institute for Materials Science and Engineering at Clausthal University of Technology is pleased to announce a postdoctoral position available for three years, with the potential for extension by an additional three years. We welcome applications from individuals who are motivated, enthusiastic, and collaborative, demonstrating a commitment to developing solutions for pressing global challenges. The salary scale for this position is EG 13 TV-L aligning with the German collective labour agreement (indicative gross monthly salary range is €4,188.00 – €6,037.00 depending on experience, family status, etc.). This opportunity is suitable for part-time work and is crafted as a qualification position for postdocs. However, we encourage outstanding candidates, including those without a PhD, to explore the opportunity to pursue a doctorate at Clausthal University of Technology.
The Institute for Materials Science and Engineering at Clausthal University of Technology has a strong application focus in Research and Teaching. The working group Digitalisation in Materials Science and Engineering has a focus on biologic, architectured materials and engineered living materials. The prospective candidate should strengthen this area strategically so that we seek a candidate with a background or interest in biological tissues.
You will find key duties, a description of your profile, what we offer, contact details, and how you can apply under https://tinyurl.com/ycxf74te. We review applications on an ongoing basis and close this advert as soon as we have found a suitable candidate. Please do not hesitate to contact us if you have any questions. We look forward to hearing from you!
The Cardiovascular Biomechanics Group at Erasmus Medical Center / TU Delft has two PhD positions available currently, both on atherosclerotic arterial wall biomechanics, one experimental and the other one computational.
Further info can be reached at https://aliakyildiz.net/vacancies/.
Application for the openings:
Position 1.) https://www.werkenbijerasmusmc.nl/en/vacancy/95506/phd-position-field-computational-vascular-biomechanics-48.24.23.tt
Position 2.) https://www.werkenbijerasmusmc.nl/en/vacancy/95504/phd-position-translational-and-experimental-biomechanics-atherosclerosis-48.23.23.tt
We are offering a 4-5-year postdoctoral position for our research line Computer methods for modeling based on finite elements and agents in multiscale simulations, within the context of the O-Health project. O-Health is a Consolidator grant from the European Research Council, awarded by the European Commission in the framework of the HORIZON Action (PREUR02822 – HEu – ERC – CoG – O-Health – 101044828) It is directed by Prof. Jérôme Noailly, from the BCN MedTech research unit of the Department of Information and Communication Technologies (DTIC), Pompeu Fabra University (UPF), Barcelona, Spain.
The researcher will be responsible for the development of the multiscale simulation platform of the O-Health project, combining finite element (organ/tissue level) and agent-based (multicellular models) models and solvers.
The researcher will gradually become responsible for the conversion of models based on the physics and biology of the BMMB, into interoperable tools within automated simulation flows, through bottom-up and top-down modeling. Likewise, he will execute and be responsible for the conversion of the models based on the physics and biology of the BMMB, into interoperable tools within automated simulation flows, for the bottom-up and top-down modeling of O-Health. You will define, program and implement workflows using and adapting existing free and open solutions, such as SBML, HDF5 and MUSCLE.
The researcher must check that the project deadlines and deliverables are met, and that the project results can be adequately disseminated through scientific media, congresses and medical journals, as well as periodically report to the PI.
Application deadline: 21/12/2023
We are hiring two ambitious and curious post-doctoral researchers in computational modeling of tendons. This position is within the ERC-funded project (Tendon_MechBio) with the scope to elucidate how mechanical loading affects tendon mechanics and tendon regeneration. The modeling will be based on unique experimental data collected within the team. We would like to employ two postdoctoral researchers with the following two aims.
- To develop detailed structural and anatomical computational models of the tendon tissue, in order to understand how mechanical loading influences tendon function, structure and composition. The computational modeling will be based on unique collected experimental data of collagen fiber structure and. The detailed structural models will be key in the project to elucidate the mechanisms guiding the tendon organ and tissue level response to load.
- To investigate how mechanical loading influences healing tendon function, structure and composition. The project includes further developing and validating an existing adaptive mechanoregulatory model for tendon repair. This will be based on collected experimental data. The developed computational scheme will be important for the project to elucidate the mechanobiological mechanisms at play.
Applicants can present preferences between aim 1 or 2, or state interest in both options.
The link to the full advertisement and application system is below:
Application deadline: 7th December
Are you looking for an exciting PostDoctoral post in Experimental Bone/Spine mechanics?
Join us at Insigneo to work with Dr Enrico Dall’Ara and Prof Damien Lacroix on the recently EU funded METASTRA project!
This highly interdisciplinary post-doctoral position will advance our understanding of the biomechanics of metastatic spine and will create an experimental database for the validation of computational models for assessing metastatic vertebrae before and after treatment.
The position is within Insigneo and is funded as part of Horizon Europe/Innovate UK research project METASTRA (https://www.metastraproject.eu/) that aims to provide a combination of computational models biomechanically validated and demonstrated in relevant clinical environments that will be incorporated in a clinical decision support system.
This part of the project is focused on model validation using state of the art mechanical testing combined with imaging and digital volume correlation.
You will have an excellent PhD in biomechanics (or a related discipline), possess a solid knowledge of bone imaging and experimental biomechanics.
Ensuring the achievement of the project objectives will advance the vision of the Insigneo institute to validate computational models for the musculoskeletal system and produce a transformational impact on healthcare.
The PDRA will also sustain and strengthen collaboration within relevant Insigneo research groups and beyond; and will commit to Insigneo’s mission to produce high quality and impactful cutting-edge research. You will join the group of Dr. Enrico Dall’Ara and Prof Damien Lacroix. Our biomechanics group within the Department has an international and interdisciplinary profile and a strong commitment to clinical and industrial translation with impact in future healthcare. We are active in biomechanics and mechanobiology of the neuromusculoskeletal systems. We have access to a fully equipped human movement analysis laboratory, a tissue testing/mechanobiology laboratory, and to ex vivo and in vivo microCT imaging facilities
Link for Applications
Deadline applications: 6th December 2023
Tentative Start: 1st March 2024
Duration: 3 years
Applications are invited from suitably qualified candidates for multiple full-time, fully-funded positions that will investigate the mechanobiology of tumour growth and therapy resistance. These positions are funded by a European Research Council Starting Grant and will be under the supervision of Dr Eoin McEvoy, Assistant Professor in Biomedical Engineering. The researcher will join Dr McEvoy’s group, which brings together expertise in biophysical modelling, active cell biomechanics, and in-vitro tumour models. The group’s overall focus is to develop advanced computational and experimental models that provide a mechanistic understanding of cell and tissue remodelling in cancer and disease, motivating novel mechano-therapeutics and treatment strategies. For further information, see www.mechanomodel.ie.
Project Description: Personalised medicine presents an exciting frontier in healthcare that tailors disease mitigation and intervention to an individual patient. This project will develop integrated experimental and computational models for the prediction of cancer patient outcomes, leveraging the biophysical forces that underpin cell behaviour. PhD research topics will bridge subcellular remodelling, single cell mechanobiology, and macroscale tumour evolution to provide a new and fundamental understanding of tumour growth and therapy resistance in breast cancer. As part of the PhD programme (project dependent), you will receive training in computational and experimental cell mechanics, patient-derived tumour organoid generation, microfluidic cell culture, advanced microscopy, agent-based modelling, and/or advanced finite element analysis.
Application Deadline: Applications will be reviewed periodically until January 31st, 2024.
We have an open PhD position at Lund University, Sweden, with focus on developing FE based simulation models for breast compression during mamography with implications for breast cancer diagnostics. Please see the link below for more information!