ESBiomech24 Congress in Edinburgh

Postdoc-Position in Biofabrication @Clausthal University of Technology

The Institute for Materials Science and Engineering at Clausthal University of Technology is pleased to announce a postdoctoral position available for one + three years (1+3 years) which we wish to fill as soon as possible. We welcome applications from individuals who are motivated, enthusiastic, and collaborative, demonstrating a commitment to developing solutions for pressing global challenges. The salary scale for this position is EG 13 TV-L aligning with the German collective labour agreement (indicative gross monthly salary range is €4,188.00 – €6,037.00 depending on experience). This opportunity is suitable for part-time work and is crafted as a qualification position for early career postdocs. However, we encourage outstanding candidates, including those without a PhD, to explore the opportunity to pursue a doctorate at Clausthal University of Technology.

The Institute for Materials Science and Engineering at Clausthal University of Technology has a strong application focus in Research and Teaching. The working group Digitalisation in Materials Science and Engineering has a focus on biologic, architectured materials and engineered living materials. The prospective candidate should strengthen this area so that we seek a candidate with a background or interest in biological tissues.

In year one, the successful candidate will support development of an EU consortium application. This includes the opportunity to start up their own research along an existing project which will commence in full from year two onwards with research in microfluidic devices, biofabrication, and bioprinting. You will find key duties, a description of your profile, what we offer, contact details, and how you can apply under https://s.gwdg.de/ECbRA8. We review applications on an ongoing basis and close this advert as soon as we have found a suitable candidate. Please do not hesitate to contact us if you have any questions. We look forward to hearing from you!

More information:

PhD in endometriosis biomechanics @Université Paris-Est Créteil Val de Marne

Location: Paris area
Laboratoire Modélisation et Simulation Multi Echelle (MSME, UMR 8208 CNRS)
Université Paris-Est Créteil Val de Marne (UPEC)
61, avenue du Général de Gaulle 94010 Créteil Cedex France

Starting date: Fall 2024

Context: Endometriosis is an inflammatory and chronic disease that affects near 1 in 10 women. It is characterized by the presence and the pathological proliferation of tissue similar to the endometrium (uterine mucosa) outside the uterus. This project partially funded by the patients’ association EndoFrance and the French Endometriosis Research Foundation (Fondation pour la recherche sur l’endométriose, EndoMeca project) targets endometriosis biomechanics. The overarching goal is to evaluate the influence of endometriosis on the distribution of forces in the abdomen, and the perception of these stresses within the pathological tissues. The role of mechanics in the development of endometriosis and patient symptoms is a subject that is mostly unexplored. However, it is evident today that endometriosis alters the mechanical properties of tissues and that these pathological developments have an impact on pelvic pain and the functioning of organs.

Objectives: The goal of the EndoMeca study is to uncover the role of mechanobiology on endometriosis physiopathology at the different scales, from cell mechanosensation to organ mechanics. The candidate will collect the first data on mechanobiology of endometriotic tissue, and subsequently provide the tools to quantify endometriosis-induced changes in local and macroscopic mechanics and biochemistry.

Within the scope of this project, three research axes will be explored over the next years. The first axis focuses on experimental work in histology and mechanics – investigating the links between the tissue mechanical behavior and the pathological micro-environment. Significant 2D and 3D data will be obtained from the analysis of biopsies through several imaging modalities. The second research axis involves image analysis including rendering, segmentation and meshing of 3D heterogeneous volumes to perform a quantitative analysis of the impact of endometriosis on various pelvic organs. The third part of the project is centered on theoretical and numerical modeling. The challenge will be to reproduce the changes in pelvic tissue geometry, microstructure and biomechanical properties through the definition of a relevant growth and remodeling law.

The candidate will be expected to conduct the research within one or several of these axes.

The candidate: The scope of this study is broad and we currently accept applications from various backgrounds: mechanical engineering, materials science / engineering, biomechanics, bioengineering, biology or image processing.

We will give priority to candidates with at least 2 of the following skills:

  • 2D/3D segmentation
  • Finite element analysis
  • Histology
  • Light/ Fluorescence Microscopy
  • Mechanics of materials
  • Programming knowledge (C, Matlab, Python…)
  • The interest in living tissue and clinical applications will be appreciated but is not necessary.

Deadline: March 29th, 2024. After that date, please contact Dr Martin as other opportunities may be available then.

How to apply: Please send your CV and cover letter to Madge MARTIN (madge.martin@cnrs.fr), Matthieu CARUEL (matthieu.caruel@u-pec.fr) and Vittorio SANSALONE (vittorio.sansalone@u-pec.fr).

4 positions at the Institute of Medical and Biological Engineering (IMBE) in Leeds, UK

The Institiute of Medical and Biological Engineering (IMBE) in Leeds, UK, is currently recruiting for 4 positions:

  1. researcher (research fellow requiring a PhD or research assistant requiring a Master) in computational damage biomechanics: https://jobs.leeds.ac.uk/vacancy.aspx?ref=EPSME1154 (for the research assistant role, check your UK working eligibility by contacting InternationalHR@leeds.ac.uk)
  2. post-doctoral research (research fellow requiring a PhD) in knee and hip biomechanical evaluation: https://jobs.leeds.ac.uk/vacancy.aspx?ref=EPSME1155
  3. PhD student in spine biomechanics: https://phd.leeds.ac.uk/project/1826-integrating-morphology-and-mechanics-developing-a-statistical-shape-and-appearance-model-ssam-for-spinal-health-assessment-intervention-planning
  4. PhD student in bone healing: https://phd.leeds.ac.uk/project/1820-computational-biomechanical-modelling-of-external-fixation-of-fractures-to-predict-bone-healing

All details of application processes are available on the respective links, deadlines within the next month.

The multi-disciplinary IMBE is embedded within the School of Mechanical Engineering and the Faculty of Biological Sciences at the University of Leeds. It is a dynamic world-renowned medical engineering research centre which specialises in research and translation of musculoskeletal and cardiovascular medical technologies that promote ’50 active years after 50’.

As a researcher or PhD student within IMBE, there will be opportunities to contribute to wider activities related to medical technologies including public and patient engagement, group training and social events. Groups of researchers working on aligned projects or using similar methods meet regularly to share ideas and best practice, and we encourage collegiate working. We will support your long-term career ambitions through bespoke training and encourage external secondments, laboratory visits or participation at international conferences.

10 PhD positions in the Europe Horizon Marie Skłodowska-Curie Project REBONE

REBONE is a four-year Doctoral Network, funded by the Europe Horizon Marie Skłodowska programme, aiming at innovatively training a new generation of researchers to develop a multidisciplinary optimization process aimed at providing technologies for personalized bone-substitute implants, based on bioactive ceramics to address the health and societal burdens of trauma and bone diseases.

The musculoskeletal system is extremely vulnerable to ageing and traumatic events, and common clinical conditions often impose a high burden on the clinical system. For patients requiring bone-substitute implants to treat critical-size bone defects, new solutions are needed to address important unmet needs: personalised solutions for better clinical outcomes; improvements in materials to ensure higher mechanical reliability without compromising bioactive and bioresorbable properties; optimised manufacturing technologies for materials and products of high reliability and quality.

In order to achieve these ambitious goals REBONE is about to open 10 fully funded PhD positions to  construct a platform of computational tools that will enable clinical experts to produce customized bone graft substitutes for the treatment of critical-size bone defects. This innovation will ensure that an ideal treatment solution is found on a patient-specific basis in terms of:

  • mechanical and mechano-biological performance,
  • surgical implantability, and
  • manufacturing process reliability.

Furthermore, REBONE will develop state-of-the-art in silico models based on advanced computational methods and advanced characterisation and validation techniques to obtain personalised implants with a surgical planning visualization system in mixed reality with the following characteristics:

  • tailored and reliable mechanical and physical properties;
  • best osteointegration capability;
  • targeted mechanical, physical and mechano-biological functions with patient-specific constraints taking into account the load-bearing anatomical location. Four selected clinical cases will be used as demonstrators of the optimization design and manufacturing processes.

LIST OF AVAILABLE PhD POSITIONS

Complete list of the 10 Doctoral positions available within REBONE:

  1. Position 1: Methods for optimization of bone-substitute architectures (Politecnico di Milano, Italy);
  2. Position 2: Micro- and macro-mechanical characterization of materials and devices and in-silico Models (Politecnico di Milano, Italy);
  3. Position 3: 3D printing technologies for Glass-Ceramic and Glass-Ceramic-based composite BTE scaffolds (Politecnico di Torino, Italy);
  4. Position 4: Tissue-scaffold biological interaction (Università del Piemonte Orientale, Italy)
  5. Position 5: Design of bone inspired scaffolds and biomechanical characterization of the bone-scaffold construct (Université de Liege, Belgium)
  6. Position 6: Industrial process for glass-ceramic device manufacturing through VPP (Lithoz GmbH, Austria)
  7. Position 7: Characterization of fracture relevant bone sites for information on the structural/compositional requirements of the implant (Ludwig Boltzmann Institute, Austria)
  8. Position 8: Models for Tissue growth and fundamental relationships with micro-architecture of scaffolds (University of Salzburg, Austria)
  9. Position 9: Biomimetic in vitro culture models for evaluation of novel bone substitute implants (University of Belgrade, RS)
  10. Position 10: Mixed reality for planning of implant surgery for bone defects of irregular shapes (MEDAPP SPÓŁKA AKCYJNA, Poland)

For info and application procedure please visit the project website https://rebone.eu/ and here:

Symposium – Theoretical and numerical developments in cellular mechanobiology – June 3 – 5 2024

We are very pleased to invite you to attend “Theoretical and numerical developments in cellular mechanobiology”, an international symposium supported by IUTAM and organized by the University of Seville (Spain). The symposium will be held during June 3 – 5 2024. In this symposium, different experts will review state-of-the-art theoretical and numerical methodologies in cellular mechanobiology. Different topics like numerical methods in mechanobiology, quantification of cellular forces or mechanics of living tissues and artificial substrates (although not restricted to) will be covered. The event will be an excellent opportunity for researchers to discuss open problems in this topic, to share different visions in this field, and to create synergies that propose solutions from our community to advance in biology and biomedicine.      

More information, including an extensive list of confirmed  keynote speakers can be found here: https://gestioneventos.us.es/congreso-iutam

Feel free to spread this within your research group and network,
Looking forward to meet you in Seville,
On behalf of the Organizing Committee

José A. Sanz-Herrera. University of Seville, Seville, Spain.
Hans Van Oosterwyck. KU Leuven, Leuven, Belgium.

Abstract submission deadline: February 29 2024
Abstract acceptance communication: March 22 2024
Registration deadline: May 27 2024
Symposium dates: June 3-5 2024

Postdoc position on the Evaluation of Interactions between Motorcyclist, Airbag and Safety Barrier via Numerical Simulations @ Université Gustave Eiffel (Lyon or Marseille, France)

The objective of this joint project (LBA & LBMC) is to integrate the barrier impact into the airbag evaluation processes of the previous REGAM project. This objective thus feeds two strategic issues:

– Quantify the combined effects of wearing an airbag vest and of a safety barrier with or without a motorcyclist screen to reduce the risk of injury during an accident (definition, analysis and choice of injury criteria in a reference case).

– Identify the area of protection (gain/limits) offered by regulatory barriers for different impact situations with the motorcyclist (sensitivity analyses).

To do this, it is a question of establishing a crash numerical modeling combining motorcyclist, motorcycle, airbag and restraint device, based on the previous work on the subject at LBA and LBMC.

More details can be found here:

https://lbmc.univ-gustave-eiffel.fr/fileadmin/redaction/LBMC/Documents/Post-doc/REGAM2_Offre_de_PostDoc_FR_ANG.pdf

Postdoc-Position in Digital Materials Science @Clausthal University of Technology

The Institute for Materials Science and Engineering at Clausthal University of Technology is pleased to announce a postdoctoral position available for three years, with the potential for extension by an additional three years. We welcome applications from individuals who are motivated, enthusiastic, and collaborative, demonstrating a commitment to developing solutions for pressing global challenges. The salary scale for this position is EG 13 TV-L aligning with the German collective labour agreement (indicative gross monthly salary range is €4,188.00 – €6,037.00 depending on experience, family status, etc.). This opportunity is suitable for part-time work and is crafted as a qualification position for postdocs. However, we encourage outstanding candidates, including those without a PhD, to explore the opportunity to pursue a doctorate at Clausthal University of Technology.

The Institute for Materials Science and Engineering at Clausthal University of Technology has a strong application focus in Research and Teaching. The working group Digitalisation in Materials Science and Engineering has a focus on biologic, architectured materials and engineered living materials. The prospective candidate should strengthen this area strategically so that we seek a candidate with a background or interest in biological tissues.

You will find key duties, a description of your profile, what we offer, contact details, and how you can apply under https://tinyurl.com/ycxf74te. We review applications on an ongoing basis and close this advert as soon as we have found a suitable candidate. Please do not hesitate to contact us if you have any questions. We look forward to hearing from you!

PhD position – FE modeling of breast compression during mamography @Lund University

We have an open PhD position at Lund University, Sweden, with focus on developing FE based simulation models for breast compression during mamography with implications for breast cancer diagnostics. Please see the link below for more information!

https://lu.varbi.com/en/what:job/jobID:662804/type:job/where:4/apply:1

PhD position in computational cardiovascular mechanics @University of Glasgow

I am looking for motivated students to join my research group and work towards their PhD in the area of computational cardiovascular biomechanics. Interested candidates are encouraged to email ankush.aggarwal@glasgow.ac.uk to discuss further. More details of the PhD position are provided below.

Project Summary: Almost 30% of all deaths globally are related to cardiovascular diseases. The overall aim of computational cardiovascular biomechanics is to help improve the diagnosis of these diseases (faster, earlier, more precise), provide better surgical outcomes, and design devices that last longer. To achieve that aim, we study the biomechanical properties of tissues and cells comprising the cardiovascular system using a combination of in-vivo imaging, ex-vivo and in-vitro testing, and in-silico modeling. Several project topics are available, which can be categorized into model development (at organ and cellular scales) and method development (based on imaging and using data science approaches). A few examples of specific projects are:

1) Predicting aneurysm development from ultrasound images using growth and remodeling simulations
2) Modeling of endothelial cells based on in-vitro experiments
3) Uncertainty quantification of biomechanical properties based on combined ex-vivo and in-vivo dataset
4) Gaussian process modeling for cardiovascular tissue mechanics
5) Development of a digital twin of the thoracic aorta

During this project, the student will have opportunities to:

  • Develop skills necessary to work at the interface of engineering and biomedical science
  • Publish papers in high-quality journals
  • Present research results at international conferences
  • Learn about nonlinear finite element analysis, nonlinear mechanics, multiscale modeling, image-based analysis, data science, and other numerical techniques
  • Learn about experimental and clinical validation
  • Collaborate with our international academic and industrial partners
  • Interact within the Glasgow Centre for Computational Engineering with other researchers (GCEC) and across departments with biomedical scientists and clinicians

Eligibility: Candidates must have an undergraduate degree in a relevant field, such as Mechanical Engineering, Biomedical Engineering, Civil Engineering, Mathematics and Computing Science, with a minimum 2.1 or equivalent final grade. A background in mechanics and knowledge of numerical methods (such as finite element analysis) would be necessary. Programming skills will be required for computational modeling.

Application: The deadline for applications is 31 January 2024, and the application process consists of two parts:
1) On-line academic application: Go to https://www.gla.ac.uk/postgraduate/research/infrastructureenvironment/ and click on the ‘Apply now’ tab. Applicants should attach relevant documents such as CV, transcripts, references and a research proposal.
2) School of Engineering EPSRC/School Scholarship Application via online portal: https://www.gla.ac.uk/ScholarshipApp/]gla.ac.uk/ScholarshipApp/ To complete the scholarship application, students will need a supporting statement from the proposed supervisor. Any queries about application procedure can be directed to eng-jws@glasgow.ac.uk

Further information: If you are interested or want more information, please contact me at my email (ankush.aggarwal@glasgow.ac.uk) before starting the formal application. Please visit Computational Biomechanics Research Group page or my staff page for more information on our research.


Corporate members of the ESB:

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