ESBiomech24 Congress in Edinburgh

Webinar: Amit Gefen / Synopsys – Computer Models in Wound Care Research

Posted on by

Wed, Jun 23, 2021 6:00 PM – 7:00 PM CEST

COVID-19 has brought the effects of pressure ulcers/injuries and device-related pressure ulcers/injuries in particular, into sharp focus. With the highly increased use of medical devices for the diagnosis and treatment of patients who require intensive care such as continuous positive airway pressure masks or ventilation and feeding tubing, and with the intense use of personal protective equipment e.g. face masks and respirators by healthcare professionals globally, the incidence of device-related tissue damage has risen starkly. This talk will explore the currently known etiology of pressure ulcers/injuries with a focus on the potential risks associated with devices used by patients and health professionals during the current pandemic. The relevant computational bioengineering research underway at the Gefen laboratory at Tel Aviv University will further be discussed.

Presenter: Professor Amit Gefen is currently a Full Professor with the Department of Biomedical Engineering at the Faculty of Engineering of Tel Aviv University and the Berman Chair in Vascular Bioengineering. The research interests of Prof. Gefen are in studying normal and pathological effects of biomechanical factors on the structure and function of cells, tissues and organs, with emphasis on applications in acute and chronic wound research. To date, Prof. Gefen published more than 270 articles in peer-reviewed international journals and multiple edited books on mechanobiology, cell and tissue biomechanics, with applications that are mostly in wound prevention and treatment.

To register click here

Webinar: THR Planning with Corin OPS and Simpleware Software

Posted on by

Title: From Virtual Pre-Operative Planning to Surgical Reality – THR Planning with Corin OPS and Simpleware Software

Date: Wednesday, October 03, 2018

Time: 11:30 AM Eastern Daylight Time

Duration: 1 hour

Summary

This webinar will explore the Corin OPS™ Total Hip Replacement (THR) system through a patient’s journey. This involves performing pre-operative patient-specific analysis to improve surgical outcomes. We will demonstrate how medical imaging is used to create a personalized plan for the surgical procedure, including patient-specific 3D printed guides. In addition, tools are provided for post-operative assessment.

We will show how Synopsys’ Simpleware™ software has been used to streamline the OPS process, capitalizing on flexible scripting capabilities to enable the development of custom tools and a bespoke robust workflow, reducing the time per surgical case required and increasing consistency and traceability.

In this webinar you will:

  • Recognize the benefits of virtual pre-surgical planning
  • Understand Corin’s OPS™ system for transforming medical images into personalized surgical plans
  • See the value of integrating Simpleware software to automate pre-surgical planning workflows

See http://bit.ly/2OMr7Nc for more details

Applications Engineer – Simpleware Software, Exeter, UK

Posted on by

Applications Engineer

18295BR

GREAT BRITAIN – Exeter

Job Description and Requirements

Overall purpose of job

Simpleware software is currently looking for a motivated applicant to join the technical support team. You should be passionate about working with image processing and 3D modelling software, and with providing technical knowledge and sales support. You will also be responsible for generating papers and promotional material which will require you to work very closely with customers and partners.

We offer a competitive salary for this position.

The closing date for this job posting is the 10th of September, 2018

Primarily, this will involve

  • Providing high quality and reliable technical support for our clients
  • Organising software demonstrations, workshops, and training
  • Visiting potential clients, and attending conferences and exhibitions
  • Generating proposals, papers, reports, press releases, software documentation, tutorials, etc.
  • Establishing new, and maintaining existing, long-term relationships with customers, partners and the media

Knowledge, experience, skills, and competencies

  • Qualified at least to first degree level in an Engineering related subject – preferably a first or 2:1
  • Experience using CAD, FEA (e.g. Abaqus, Ansys, Comsol, etc.) or CFD (e.g. Fluent, OpenFOAM, etc.) codes
  • Good knowledge of either image processing, biomechanical or materials modelling
  • Excellent presentation, communication and interpersonal skills
  • Strong personal organisation, with good project management skills and ability to work to deadlines
  • Strong project management ability, personal organisation and customer focus
  • Self-motivation and ability to work on own initiative whilst being a team player
  • Knowledge of scripting languages (e.g. Python) and web technologies (HTML, CSS, Java Script, PHP and MySQL) would be useful/an advantage

further details and apply online

PhD Project – Cardiff / Synopsys Inc Exeter, England, United Kingdom

Posted on by

Job description

Synopsys NE Ltd (https://www.synopsys.com/simpleware.html) invites applications for an Early Stage Researcher position (Doctoral Candidate) as part of the Rapid Biomechanics and Simulation for Personalized Clinical Design (RAINBOW) MCSA European Training Network. RAINBOW is funded under the European Union’s Horizon 2020 research and innovation program.

The post holder will be employed on a fixed term (36-month contract) and be principally based at the Synopsys-Simpleware offices in Exeter UK but will also be enrolled as a full time graduate student at Cardiff University (http://www.cardiff.ac.uk/) undertaking research towards a PhD degree award. The candidate will be expected to spend periods of time in Cardiff as well as with other partners in the consortium.

The post holder will develop numerical methods to simulate the deformations of soft-tissues in the context of computer-aided surgery. In particular, he/she will contribute to bridging the gap between advanced 3D imaging techniques and physics-based computer simulations in order to improve current capabilities in the area of computer-aided diagnostic and surgical planning. A thorough knowledge of software development is essential.

This is a full time (37.5 hours per week) position on a fixed term basis for a fixed-term of 36 months.

See https://www.linkedin.com/jobs/view/755835607/ for further details

PhD Project – Luxembourg / Synopsys Inc Exeter, England, United Kingdom

Posted on by

Job description

Synopsys NE Ltd (https://www.synopsys.com/simpleware.html) invites applications for an Early Stage Researcher position (Doctoral Candidate) as part of the Rapid Biomechanics and Simulation for Personalized Clinical Design (RAINBOW) MCSA European Training Network. RAINBOW is funded under the European Union’s Horizon 2020 research and innovation program.

The post holder will be employed on a fixed term (36-month contract) and be principally based at the Synopsys-Simpleware offices in Exeter UK but will also be enrolled as a full time graduate student at the University of Luxembourg (https://wwwen.uni.lu/) undertaking research towards a PhD degree award. The candidate will be expected to spend periods of time in Luxembourg as well as with other partners in the consortium.

The post holder will develop numerical methods to simulate the deformations of soft-tissues in the context of computer-aided surgery. In particular, he/she will contribute to bridging the gap between advanced 3D imaging techniques and physics-based computer simulations in order to improve current capabilities in the area of computer-aided diagnostic and surgical planning. A thorough knowledge of software development is essential.

This is a full time (37.5 hours per week) position on a fixed term basis for a fixed-term of 36 months.
See https://www.linkedin.com/jobs/view/755834914/ for further details.

PhD: mechanics of a synthetic elastic protein and effects on arterial function @ Lyon

Posted on by

Doctoral thesis at the Center for Biomedical and Healthcare Engineering

Mines Saint-Etienne – SAINBIOSE (INSERM-U1059) – Université de Lyon (France)

 

Mechanical characterization and modeling of a synthetic elastic protein and its effects on the arterial function

 

Keywords: biomechanics, multiscale models, homogenization, elastin, mechanical characterization, tissue engineering.

 

Scientific context: Elastin is the main elasticity provider for several soft tissues (such as dermis, arteries, pulmonary alveoli) in its fibrous form and a signaling molecule in cell/extracellular matrix interaction. Elastin-rich elastic fibers allow the large artery walls to transform the pulsatile blood flow ejected by the heart into a continuous blood flow in the peripheral arteries (Windkessel effect). Dysfunctions are highly correlated with diseases such as artery stenosis, aneurysm, hypertension or cardiac hypertrophy, which have strong repercussions on arterial biomechanics and can threaten the vessel integrity.

Setting aside surgery, there is currently no treatment for preventing, blocking or treating any loss of elasticity. It therefore appears, from a biomechanical point of view, that the introduction of an entity that provides elasticity within the arterial wall would be the most trivial action to stop arterial stiffening, but remains currently limited due to chemo-biological issues. The Arterylastic project, to which the thesis is linked, proposes to unlock this technological barrier using an original synthetic elastic protein (SEP) recently developed with a synthetic backbone devoted to skin engineering.

 

Academic context: As previously mentioned, the thesis takes place in a larger project named Arterylastic, funded by ANR, combining pluridisciplinary approaches of three laboratories in France: LBTI – the Laboratoire de Biologie Tissulaire et Ingénierie Thérapeutique (UMR5305 CNRS/UCBL1 Lyon), HP2 –Hypoxie Physiopathologie Cardiovasculaire et Respiratoire (INSERM U1042 – University Grenoble Alpes) and Sainbiose (within the Center for Biomedical and Healthcare Engineering CISSAINBIOSE/INSERM U1059 – Mines Saint-Etienne). The PhD student will work at CIS, which also conducts major international research projects in the field of soft tissue biomechanics, in particular aortic aneurysms. He will collaborate with other researchers involved in ERC projects (https://www.mines-stetienne.fr/en/author/avril/, https://www.emse.fr/~badel/).

 

Objectives: The objective is to restore (or at least improve) arterial function and mechanical properties under conditions of elastic fibers injury. The objective will be reached if the SEP is correctly integrated into elastic fibers and if the SEP restores arterial wall elasticity and/or physiological parameters in relevant animal models. In this thesis, we will evaluate the mechanical behavior of the cross-linked SEP and of arterial samples from treated mouse models and a numerical model will be developed from experimental data to better predict treatment parameters.

The main tasks will be:

  1. Experimental tests will be carried out for characterizing the macroscopic mechanical properties of the SEP and of arteries treated with the SEP. The cross-linked SEP will be characterized using tensile tests with a customized device. Mechanical parameters of treated arteries will be assessed by measuring pressure-diameter curves from mouse arteries tested in a customized tension-inflation test.
  2. A multiscale numerical model of the mechanical behavior of arteries will be elaborated, taking into account their microstructural composition and morphology (bilayer, specific contributions of elastin, collagen, smooth muscle cells, possible proteoglycans) and including the effects of possible grafting of the SEP to the arterial wall. The model will be tested for arteries with competent elastic fibers, for arteries with damaged elastin and induced-tissue remodelling, and for arteries treated with the SEP.
  3. The experimental results obtained at task 1 will be used to evaluate and calibrate the prediction ability of the numerical model developed in task 2. Sensitivity analysis permitting to find the optimal treatment conditions with the SEP for different types of therapeutic targets will be addressed.

 

Candidate profile: Candidates with strong skills in mechanics (modeling and experimental) and biomechanics are expected. Motivation and interest in bioengineering applications is recommended.

 

How to apply:Send CV, cover letter and letters of recommendation to claire.morin@emse.fr and avril@emse.fr.

Canada Research Chair (Tier I), Mechanisms of Concussion, University of Calgary

Posted on by

The Faculty of Kinesiology at the University of Calgary invites applications for a tenured Professor appointment as a Natural Sciences and Engineering Research Council (NSERC) Tier 1 Canada Research Chair (CRC) in Mechanisms of Concussion.  Further information about the Canada Research Chairs Program can be found on the Government of Canada’s CRC website, including eligibility criteria.  The appointment date for the successful candidate is anticipated to be between January and July 2019.

The full job posting can be found here.

Open Position: Biomechanics and Proteomics at TU Wien

Posted on by

Open Position for a University Assistant in Biomechanics and Proteomics

 

Description:                            The Institute of Lightweight Design and Structural Biomechanics (ILSB) of TU Wien invites applications for the position of a University Assistant in the area of biomechanics and protein analysis. The mechanics of biological tissue are closely related to their hierarchical structure and composition. For example the absence of certain noncollagenous proteins in bone has been shown to be deleterious for fracture toughness. Similarly, the presence of sugar-mediated cross-links in collagen within bone as well as in musculoskeletal soft tissues such as tendons or ligaments is thought to alter their material properties. The candidate sought for this position will work at the cross-roads of tissue composition and mechanics, whereby the compositional aspects will be investigated via mass-spectrometry methods under supervision of Prof. M. Marchetti-Deschmann of the Institute of Chemical Technologies and Analytics of TU Wien. A special focus will be on the compositional aspects of the enthesis (the tendon-to-bone-junction) as well as on tendon and isolated individual collagen fibrils. Mechanical tests will be conducted mostly with via atomic force microscopy in the Interfacultary Laboratory for Nano- and Micromechanics of Biological and Biomimetical Materials, employing where the ILSB is a major stakeholder. In addition to conducting research towards a PhD degree the post will also entail participation in administrative tasks and teaching activities at the ILSB.

Qualifications:                      We are looking for an individual with a completed MSc in Biomedical Engineering, Physics or a related discipline. Skills and knowledge in biomechanics, biochemistry, chemical analysis will be advantageous. Further, German language skills (native speaker or level B2 according to CEFR) are required.

Further information:              For informal discussions contact Professor Philipp Thurner, pthurner@ilsb.tuwien.ac.at

How to apply:                          Send applications to rene.fuchs@tuwien.ac.at no later than March 9th 2018

European Calcified Tissue Society Webinar: bone implant interface

Posted on by

ECTS Academy Webinar: Multiscale characterization of the biomechanical properties of the bone-implant

Live Webinar: 29 November 2017, 3-4pm CET

Webinar objectives:

Learn about the cutting-edge science and career paths of the most successful young scientists in Europe
Ask questions to better develop your own career plan
Learn from the questions of peers
Benefit from the knowledge of speakers on how to apply for ERC grants

Format:

25 min science presentation
10 min presentation of the career path
25 min Q&A

Speaker:

Dr. Guillaume Haiat

ECTS Academy Webinar

Corporate members of the ESB:

AMTI force and motion logo
BERTEC logo
Beta CAE logo
BoB Biomechanics logo
Materialise logo
Nobel Biocare logo