ESBiomech24 Congress in Edinburgh

Two open post-doctoral positions @Lund University

We have two open post-doctoral positions in our team – one experimental related to image analsyis of soft knee tissues, and one numerical related to computational modeling of tendon mechanics. 

1: Experimental synchrotron imaging of soft knee tissues:

We are looking for a post-doctoral researcher focusing on synchrotron imaging and image analysis to join our team.  The goal for the post-doc is to develop, perform and primarily analyze data from high resolution experimental imaging of soft tissues, acquired mainly using synchrotron phase contrast X-ray tomography, but also other imaging modalities. The goal includes characterizing meniscus and cartilage microstructure and its relation to loading, based on in situ loading experiments during imaging.

The link to the full advertisement and application system is below:

https://lu.varbi.com/en/what:job/jobID:631105/type:job/where:4/apply:1

Application deadline:  6th of July

Please contact Prof. Hanna Isaksson (hanna.isaksson@bme.lth.se) with any questions.

2: Numerical modeling of achilles tendon mechanics and/or mechanobiology:

We are looking for a post-doctoral researcher in computational modeling of tendons. This position is within a larger ERC-funded project (Tendon_MechBio) with the scope to elucidate how mechanical loading affects tendon mechanics and tendon regeneration. There is a possibility to employ up to two postdoctoral researchers with the following two aims. 

  1. To investigate how mechanical loading influences healing tendon function, structure and composition. The project includes further developing and validating an existing adaptive mechanoregulatory model for tendon repair. This will be based on collected experimental data. The developed computational scheme will be important for the project to elucidate the mechanobiological mechanisms at play. 
  2. To develop detailed structural and anatomical computational models of the tendon tissue, in order to understand how mechanical loading influences tendon function, structure and composition. The computational modeling will be based on unique collected experimental data. The detailed structural models will be key in the project to elucidate the mechanisms guiding the tendon organ and tissue level response to load. 

Applicants can present preferences between aim 1 or 2, or state interest in both options.

The link to the full advertisement and application system is below:

https://lu.varbi.com/en/what:job/jobID:630270/type:job/where:4/apply:1

Application deadline: 6th of July

Please contact Prof. Hanna Isaksson (hanna.isaksson@bme.lth.se) with any questions.

PhD candidate on lattice structures applied to improve prosthetic sockets for amputees @University of Navarra

Description:

Amputee cases increase due to vascular diseases between elderly people, and mainly due to traffic accidents or war injuries in younger people. A prosthetic socket is the critical interface between a person’s body and their prosthetic device. Prosthetic sockets are traditionally made by rigid materials, which are not thermoregulatory and cause irritations, wounds and ulcerations. Hence, amputee comfort is still a challenging research field.

This position offers the possibility of researching in innovative lattice structures to design and optimise traditional sockets, and hence improve quality of life of the increasing young amputee population in the world.

Department:

Department of Mechanical Engineering and Materials of Tecnun, the Engineering School of the University of Navarra. During the PhD, the student will have the opportunity to do a placement at a foreign university or research center. The research project will be carried out in collaboration with the Clinica Universidad de Navarra.

Requirements:

– Master Degree in Mechanical Engineering or similar degrees.

– Language: Highly proficient in English.

– Software: Finite Element software (ABAQUS), basic programming in Matlab, Python, Computer Aided Design software (Rhinoceros, Grasshopper, CREO).

– To have initiative for research.

Offered:

Tecnun, the Engineering School of the University of Navarra offers a 4-year doctoral contract at the Technological Campus in San Sebastian (Spain).

Thesis should be completed in 4 years.

Start date: As soon as possible.

Documentation:

Send the following documentation by email to alopez@unav.es: cover letter describing your motivation as a thesis candidate; updated CV; undergraduate and Master’s degree transcripts.

Postdoc position on Computational modeling of drug-toxin interactions in the kidney @Maastricht University

The department of Cell Biology-Inspired Tissue Engineering (cBITE) at the MERLN Institute for Technologyinspired Regenerative Medicine at Maastricht University in the Netherlands invites applications for a postdoctoral position. The post-doctoral researcher will perform cutting-edge research in computational modeling methods applied to drug-toxin interactions in the kidney. Chronic kidney disease (CKD) is one of the top ten causes of death worldwide. Gradual decline in kidney function leads to accumulation of metabolic waste products (toxins) normally excreted by the kidneys, contributing to progression of CKD and its comorbidities, in particular cardiovascular disease. To alleviate the CKD complications, patients are routinely treated with many drugs, such as antihypertensive and cholesterol-lowering agents. However, the transporter proteins in kidney cells that handle these drugs are also responsible for secreting the toxins, and may, therefore, not be able to handle the competing demands. Considering the multitude of CKD drugs, toxins and transporter proteins and their potential interactions, investigating drug-toxin interactions is experimentally time consuming and difficult to accomplish. In this project, funded by the Dutch Kidney Foundation (https://nierstichting.nl/), we propose to integrate computational and experimental expertise with state-of-the-art technologies to address investigate drug-toxin interactions in the kidney and improve CKD drug treatments.

Project description: 

  • Computational modeling of drug-toxin transport in the proximal tubule; (competitive) binding kinetics;
  • Sensitivity analysis;
  • Analysis and integration of various in vitro/in vivo data for model calibration;
  • Parameter optimization.

Application deadline: 29 June 2023

More information:

https://www.academictransfer.com/en/328781/postdoc-position-merln-computational-modeling-of-drug-toxin-interactions-in-the-kidney/

PhD Scholarship: A computational platform for understanding bone structure optimisation @QUT/MSME

Institutes: Queensland University of Technology (QUT, Australia), and University of Paris Est Creteil (UPEC, France) — Multiscale modeling and simulation lab (MSME UMR 8208 CNRS).

Supervisors: Prof. Peter Pivonka (QUT, peter.pivonka@qut.edu.au) and Prof. Vittorio Sansalone (MSME UPEC, vittorio.sansalone@u-pec.fr)

Résumé: We seek to better understand how cortical bone is affected by osteoporosis and drug treatments. The successful PhD candidate will develop state-of-the-art computational models of bone remodeling to predict changes in cortical porosity and bone matrix properties due to osteoporosis and other treatment regimens. The in-silico results will be validated by experimental data provided by Prof David Cooper (USASK). Project areas include:

• Development of continuous, i.e. based on partial differential equations, models of bone remodeling to investigate the behaviour of basic multicellular units (BMUs) in cortical bone;

• Development of discrete, i.e. cellular automata based, models of BMU behaviour in cortical bone;

• Development of multiscale models of bone remodeling and adaptation that are able to predict changes in cortical porosity and bone tissue mineral density distribution.

Closing date: Applications will be accepted until the scholarship is awarded, but applications will be assessed starting June 25th, 2023.

More information (salary, essential and desirable criteria, etc.):

PhD position on hip biomechanics using statistical shape models @Lund University

The biomechanics group at Lund University, Sweden, is looking for a PhD student to investigate hip biomechanics using statistical shape models. This is a fully funded PhD position and applications must be sent through the official recruitment portal: https://lu.varbi.com/what:job/jobID:630169/?lang=en.

Deadline: June 23rd, 2023

More information:

New master course on musculoskeletal system, locomotion & exercise @Lyon University

Please find below the brochure for a new Master’s course (2nd year) to be opened at Lyon 1 University in 2023. This is an international course, intended to welcome foreign students (teaching in English) of a good level, wishing to learn about research in the field of the musculoskeletal system (in the broad sense). Scholarships are provided to students and a great emphasis is placed on immersion in the research laboratories.

Application deadline: June 19, 2023.

2 positions on imaging and biomechanics in spine surgery planning @SKAIROS

SKAIROS is a deeptech startup which aim is to translate subject specific finite element spine models to the real life, to help for spinal implants design and surgery planning.

More information on the two job descriptions:

PhD position in biomechanics / simulation / metamodeling @Université Eiffel Lyon

This is an offer for a PhD topic at Univ Eiffel in Lyon France in collaboration with major industrial partners:

Title: Towards a more equitable protection of vehicle occupants: combining human body models and metamodeling techniques to improve safety

Start date: October 2023.

Keywords: Biomechanics, Finite element modelling and simulation, Metamodeling, Machine learning

Academic environment and work place: Laboratory of Biomechanics and Impact Mechanics, Univ. Eiffel, Lyon France

Industrial partners: Autoliv (Gothenburg, Sweden), LAB PSA Renault (Nanterre, France).

See document for details and contact information:

14 PhD positions in spine biomechanics @University of Bologna

The call includes 14 positions.  We have four projects in the field of Biomechanics:

  #2 Towards digital diagnosis: models for the evaluation of the intervertebral disc (supervisor: prof. Luca Cristofolini)

  #3 Prevention of vertebral fractures: digital diagnosis and computational modelling of vertebrae affected by metastasis (supervisor: prof. Luca Cristofolini)

  #4 Digital twins to prevent the risk of joint replacement failure in patients affected by neurodegenerative disorders (supervisor: prof. Marco Viceconti)

  #5 Digital twins informed by wearable sensors to predict joint loads in the real world (supervisor: prof. Marco Viceconti)

All the positions are within the PhD program in Health and Technology, a highly interdisciplinary program which includes supervisors from the different domains.  The call is closing on 20 June, to start on 1st November 2023.  

https://www.unibo.it/en/teaching/phd/2023-2024/health-and-technologies

More information:


Corporate members of the ESB:

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