Simulation cell extrusion in bioprinting by Gianluca Santesarti, University of Rome Tor Vergata.
Extrusion bioprinting is a challenging additive manufacturing process of bioengineering in which cells are printed through a non-Newtonian polymer to reproduce an organ-like scaffold. Due to its complexity and the influence of several process variables, computational models would allow to reduce the experimental optimization costs and increase the process innovation. This figure shows a simulation of cells extruded through a standard nozzle used in bioprinting. Due to the cross-section reduction, there is an increment of the fluid velocity which determines an increment of shear stresses acting on cells which in turn are strictly related to cell viability.
