Category Archives: PhD/Master student positions

5 PhD positions @ MatureTissue

MatureTissue – https://dc-mature-tissue.at

CALL IS OPEN! APPLY HERE: https://dc-mature-tissue.at/application/

OPEN APPLICATION

MatureTissue offers a 4-year (48 months) employment contract for early stage researchers (PhD positions).
The goal of the DC MatureTissue is to train future leaders who will bridge engineering and biology to find solutions for a healthy and aging society.

APPLY HERE: https://dc-mature-tissue.at/application/

WHAT ARE THE GOALS?

Research into healthy aging not only means to investigate fast killers, like cancer or SARS-CoV-2, but also the musculoskeletal aches in our bodies. Aches may start small, but they can become severe and significantly impair the quality of life, especially at older age. This is a clear unmet clinical need, and well-documented joint research interest of the MatureTissue faculty members. MatureTissue is perfectly aligned with the overall research strategies of the Technikum Wien and TU Wien.

MatureTissue is underpinned by a consortium of researchers from the Technikum and TU Wien bringing together both applied and basic science focus; only by this bundling of expertise all essential topics are covered: bioreactorsmicrofluidicsbiomechanics, molecular biologyand analytical chemistry. We, the MatureTissue faculty, want to recruit 5 outstanding PhD students and work together to address important challenges of musculoskeletal conditions by maturing 3D cell constructs to functional artificial tissues of bone, tendon, cartilage and muscle by controlled mechanical stimulation.

PhD studentship on the mechanobiology of fibrosis using multiscale mechanics and imaging @Queen Mary University of London

The Institute of Bioengineering (IoB) at Queen Mary University of London (QMUL) has a fully-funded EPSRC PhD studentship on understanding the biomechanics of cutaneous fibrosis. Fibrotic scarring affects >100 million people every year, and targeted therapies do not currently exist. Fibrotic progression is critically influenced by the nanoscale mechanics of the fibrillar collagen network, but these mechanisms and their link to the cellular response are unclear. This project will uncover the nanoscale tissue-matrix biophysics and link to the fibroblast repair response, by combining micromechanics, in situ synchrotron small-angle X-ray scattering and correlative functional imaging on an animal model.  It is a collaborative project between experts in i) nanoscale tissue mechanics (IoB-QMUL) and ii) the biology of fibrosis (at the William Harvey Research Institute, QMUL).

More information: https://www.findaphd.com/phds/project/uncovering-the-nanoscale-biophysics-of-cutaneous-fibrosis/?p139312

PhD project on “Novel computational modelling for personalised treatment of osteoarthritis” @University of Edinburgh

An exciting fully funded PhD opportunity in collaboration with an industrial partner, 3D Metal Printing Ltd, is available at the University of Edinburgh. The project is in the area of biomechanics and is entitled “Novel computational modelling for personalised treatment of osteoarthritis”.  The project requires good mechanics and finite element modelling abilities. The project description is at:

https://www.ed.ac.uk/usher/precision-medicine/app-process-eligibility-criteria/22-23-projects/novel-computational-modelling-for-personalised-tre

Applicants can apply at: https://www.ed.ac.uk/studying/postgraduate/degrees/index.php?r=site/view&id=919

Eligibility is available at:

https://www.ed.ac.uk/usher/precision-medicine/app-process-eligibility-criteria

As you will see that oversees applicants are also eligible to apply.

If you are interested please contact me at pankaj@ed.ac.uk with your CV in the first instance.

Also note the deadline for applications is 20th January 2022.

2 PhD positions on computational modeling of blood vessel formation @TU Eindhoven

Are you fascinated by predictive computational modelling?

Are you eager to apply mathematics to a biomedical setting?

Then you might be our next PhD candidate in Biomedical Engineering!

More information can be found here:

https://jobs.tue.nl/en/vacancy/phd-in-biomedical-engineering-905587.html

https://jobs.tue.nl/en/vacancy/phd-in-biomedical-engineering-905597.html

PhD position on investigating mechanical loading effects on postnatal development of articular cartilage @University College Dublin

Funding is available for a fully funded PhD position in UCD in Ireland from May or September 2022. Candidates can be from anywhere in the world. The project will be in close collaboration with the UCD Veterinary School and co-supervised by Prof Nowlan and by Prof Brama. The studentship includes stipend of €18,000 per annum (tax free) and fees (EU or international). Funding is available for four years.

Applicants should have a first class or upper second class degree (ideally a Masters) in Biomedical Engineering, Biomedical Science, Medical or Veterinary Sciences, or a closely related discipline. Candidates should have a keen interest in working with translational animal models, and also in the biomechanics of the musculoskeletal system.

This PhD project will investigate how mechanical loading affects postnatal development of articular cartilage in a goat model system. The research will involve an exciting combination of biological, imaging and engineering techniques. There will be opportunities for international travel and collaboration. 

To apply, please send a CV and a cover letter summarising your experience and your interests in this specific PhD project to Prof Nowlan. The position is open until filled. 

Website: https://developmental-biomechanics.org/contact/

PhD position in computational cardiovascular biomechanics @University of Glasgow

I am looking for motivated students to join my research group and work towards their PhD in the area of computational cardiovascular biomechanics. Interested candidates are encouraged to email ankush.aggarwal@glasgow.ac.uk to discuss further. More details of the PhD position are provided below.

Project Summary: Almost 30% of all deaths globally are related to cardiovascular diseases. The overall aim of computational cardiovascular biomechanics is to help improve the diagnosis of these diseases (faster, earlier, more precise), provide better surgical outcomes, and design devices that last longer. To achieve that aim, we study the biomechanical properties of tissues and cells comprising the cardiovascular system using a combination of in-vivo imaging, ex-vivo and in-vitro testing, and in-silico modeling. The projects can be divided into model development (at organ and cellular scales) and method development (based on imaging and using data science approaches). A few examples of specific projects are:

1) Multiscale modeling of the heart muscle
2) Modeling of endothelial cells based on in-vitro experiments
3) Developing methods for biomechanical characterisation of tissues from ultrasound images
4) Designing optimal experiments for cardiovascular tissues under uncertainty

During this project, the student will have opportunities to:

  • Develop skills necessary to work at the interface of engineering and biomedical science
  • Publish papers in high-quality journals
  • Present research results at international conferences
  • Learn about nonlinear finite element analysis, nonlinear mechanics, multiscale modeling, image-based analysis, data science, and other numerical techniques
  • Learn about experimental and clinical validation
  • Collaborate with our international academic and industrial partners
  • Interact within the Glasgow Centre for Computational Engineering with other researchers (GCEC) and across departments with biomedical scientists and clinicians

Eligibility: Candidates must have an undergraduate degree in a relevant field, such as Mechanical Engineering, Biomedical Engineering, Civil Engineering or Mathematics, with a minimum 2.1 or equivalent final grade. A background in mechanics and knowledge of finite element modeling would be necessary. Programming skills will be required for computational modeling.

Application: The deadline for applications is 31 January 2022, and the application process consists of two parts:
1) On-line academic application: Go to https://www.gla.ac.uk/postgraduate/research/infrastructureenvironment/ and click on the ‘Apply now’ tab. Applicants should attach relevant documents such as CV, transcripts, references and a research proposal.
2) The scholarship application: Complete the application form found at the following webpage: https://www.gla.ac.uk/media/Media_815227_smxx.docx and attach a letter of support from a potential supervisor. Both the application form and supporting letter should be emailed to eng-jws@glasgow.ac.uk

Further information: If you are interested or want more information, please contact me at ankush.aggarwal@glasgow.ac.uk before starting the formal application. Please visit Computational Biomechanics Research Group page or my staff page for more information on our research.

EU-funded Doctoral College ENROL – Engineering of Life Sciences @TU Wien

ENROL – Engineering for Life Sciences https://www.tuwien.at/en/enrol

CALL IS NOW OPEN! APPLY HERE: https://tuwien.bewerberportal.at/Job/167223

ENROL is an interdisciplinary Marie Skłodowska-Curie COFUND doctoral programme at Technische Universität Wien that is set up to educate and train a new generation of 20 high achieving early stage researchers (ESRs) to study and develop novel technologies and engineering solutions for the life sciences. 

ENROL is set out for a total duration of 5 years (60 months) with a 3-year (36 months) employment contract for the ESRs.

ENROL’s long-term goal is to empower ESRs to become future leaders in academia and industry, as well as entrepreneurs capable of setting up their own spin-off companies. The education philosophy of ENROL is based on creativity, curiosity, ability, and passion.

Training Europe’s next top Engineers for Life Sciences

Over the last few years, the fields of life sciences and engineering sciences have mutually fertilized each other to a level, where cell biological samples have become major stimuli for engineers, and in turn novel technological inventions have become key driving forces that triggered discoveries in the life sciences. In the ENROL DP we want to push forward these ground-breaking developments by training next generation, multidisciplinary graduates for frontier research across faculties and disciplines at the interface of engineering and the life sciences. Our programme integrates/reunites a broad spectrum of scientific and technological fields related to molecular bioengineering, biophysics & biochemistry, biomechanics, biological imaging, biomaterials, computational modelling, and tissue engineering, offering the PhD students life-long flexibility for continued professional growth. Current limitations in our understanding of cellular interfaces are mainly due to the complexity of the natural environment of a cell, including tissue- or cell-type specific parameters. Furthermore, research on this topic has been hampered by technical and experimental challenges for the characterization of the surfaces and the cellular response, and by insufficient theoretical models. As a particular scientific focus, ENROL aims at engineering functional interfaces between inorganic and bio-organic systems in order to push them towards new levels of understanding and technological applications.

You can find pitch videos of the advertised PhD topics here (https://www.tuwien.at/en/enrol/research-projects). Specifically, the following two topics have a strong biomechanics aspect:

More information:

2 PhD positions in Biomedical Engineering with focus on mechanobiological modeling @Lund University

Mechanobiological modeling of regeneration and degeneration of soft musculoskeletal tissues

General description: The research in the biomechanics group is focused on understanding the link between mechanics and biology in the musculoskeletal system, including related pathologies and repair of skeletal tissues. Experimental studies, tissue characterisation, imaging and computational simulation techniques are used. The research is applied to problems in orthopaedics to develop better methods to understand and improve repair of musculoskeletal tissues.

Soft musculoskeletal tissues (knee joint tissues and tendons) all connect or transmit forces during movement in the body. Despite having specialized mechanical functions and tailored microstructures, they present with a similar gross composition based on a collagen network, small amounts of proteoglycans, and an extensive amount of water. In these projects we are looking to develop adaptive computational models of how the tissues respond and adapt to mechanical loading over time, and specifically how mechanical stimulation affects the tissue’s regenerative capacity after damage and the degenerative degradation in response to injury. We are looking for 2 PhD students to be dedicated to the following projects:

Project 1:  Tendons connect muscles to bones and enable energy-efficient locomotion. The Achilles tendon is the largest and the most injured tendon in the human body. Ruptures often occur during recreational sport activities but can also be a result of ageing. Mechanical loading is a prerequisite for tendon healing. Controversial and often unsuccessful treatments of tendon ruptures could be improved by elucidating how loading affects the mechanobiological aspects of tendon healing. This position is within a larger project with the scope to elucidate how mechanical loading affects tendon regeneration.

The aim for PhD student 1 is to investigate how mechanical loading influences healing tendon function, structure and composition. The project includes to further develop and validate an existing adaptive mechanoregulatory model for tendon repair. This will be conducted based on collected experimental data from ongoing studies. The developed computational mechanobiological scheme will be key in the project to elucidate the mechanobiological mechanisms at play.

PhD student 1 would be actively working within the group and with collaborators within the TENDON_MECHBIO project funded by the European Research Council.

Project 2: Osteoarthritis (OA) is a common joint disease affecting over 40 million Europeans. The number of patients with OA will increase by over 70% in developed countries during the next 20 years, while direct and indirect costs are estimated to increase by over 300%. The most cost-effective and helpful treatment for the disease would simply be prevention. Since the progression of OA is highly subject-specific, prevention of the disease can only be possible when the progression can be predicted for an individual patient. The position is within a project with the overall aim to develop a tool to predict the onset and progression of osteoarthritis in the knee joint tissues due to daily loading conditions. The consortium will combine patient-specific motion analysis and computational modelling approaches for OA diagnostics, personalized prediction, and optimal treatment.  

The goal for PhD student 2 is to develop and implement constitutive material models and mechanobiological adaptive models of knee joint tissues in a finite element based mechanobiological framework of the knee. The framework will be validated against tissue specific experimental and clinical data available within the collaborative network and overall prediction of tissue degeneration during OA. 

PhD student 2 would be actively working with international collaborators within the MathKOA project funded by NovoNordisk Foundation.

Approach: Both projects include designing and developing numerical framework, followed by simulations and data analysis. Understanding and utilizing experimentally available data is important.

The full advertisement together with the link for applications is available on: 

https://lu.varbi.com/en/what:job/jobID:439902/type:job/where:4/apply:1

PhD position on computer mechanobiology of spinal surgery @Charité

A PhD position is available within the Computational Mechanobiology Group at the Julius Wolff Institute (Charité – Universitätsmedizin Berlin). This position is funded through a research grant from the German Research Foundation (DFG) to investigate the mechanobiology of tissue regeneration following different spinal surgical interventions. The work will be carry out in the framework of a national consortium (DFG funded Research Unit) where clinicians, engineers, material scientists, mathematicians and biologists will be investigating the dynamics of the spine in healthy and pathological conditions and its relation to low back pain. Research goals will be addressed using computer modeling approaches coupled to in vivo and in vitro experimental data that will be provided by consortium partners.


The successful candidate will have a strong background in one or more of the following areas: mechanics, computational biology and/or computational mechanics. Strong programming and computer modelling skills are required. The position is available for three years.


The work will be conducted in a highly interdisciplinary research environment. As a PhD student, you will be associated to the Berlin-Brandenburg School of Regenerative Therapies (www.bsrt.de) and benefit from the interaction with international scientists.

Interested candidates should submit their application including two references by October 1st, 2021. Applications should be sent to: Prof. Sara Checa (sara.checa@charite.de)

PhD position on Computational model of guided growth in immature skeleton for custom-made correction of deformities @Universitat Pompeu Fabra

Limb deformities in children motivate frequently pediatric orthopedic consultations, because of angular (genus valgus / varus), torsional (internal / external torsion) or longitudinal (leg length discrepancy) bone growth disorder, or combinations thereof. We currently apply guided growth techniques with implants that temporarily block the physis. These techniques correctly solve genu valgus but are not as effective for genu varus or leg length discrepancy and are not effective for torsional or combined deformities. In addition, these techniques often lead to complications such as the emergence of deformities in other planes or the change of epiphyseal joint shape.

The objective of the present PhD project is to create a computational model of physical growth that allows to customize the treatment of a specific deformity through individualized designs of implant and the ability of the devices to correct the deformity with the greatest efficiency and the shortest time. It is part of a larger scale project that combines the physeal surgery in experimental animal (pig) and computer developments for the simulation model of physial growth, in collaboration with the children Hospital Sant Joan de Deu (SJDD), Barcelona.

The computational model development stands for the core of the proposed PhD thesis at BCN MedTech. It will combine image analysis and mechanobiological theories of epiphyseal bone growth, through finite element modelling, to simulate different growth guidance systems made of plates or screws. The model will be uniquely calibrated and validated against it ability to recreate and correct deformities against the experimental animal model. Eventually, it will be transferred to the physiological characteristics of the human bone, leading to a pipeline of models and simulations to properly plan the surgical correction of growth deformities in patients.

More information can be found here:

Application: Please send: · Full CV · motivation letter · two reference letters · Academic transcripts to jerome.noailly@upf.edu by August 31th, at the latest.