Category Archives: News

General news articles from the ESB.

PhD position on Computer mechanobiology of mandibular reconstruction @Charité

A PhD position is available within the Computational Mechanobiology Group (Prof. Sara Checa) at the Julius Wolff Institute (Charité – Universitätsmedizin Berlin). This position is funded through a research grant from the German Research Foundation (DFG) to investigate the biomechanics of mandibular reconstruction with fibular free flap. The aim is to use computer modeling approaches supported by clinical data to understand the mechanical conditions promoting mandibular repair.

The successful candidate will have a strong background in one or more of the following areas: mechanics, computational biology and/or computational mechanics. Strong programming and computer modelling skills are required. The position is available for three years.

The work will be conducted in an interdisciplinary research environment composed of engineers, biologists and clinicians. As a PhD student, you will be associated to the Berlin-Brandenburg School of Regenerative Therapies ( and benefit from the interaction with international scientists.

Interested candidates should submit their curriculum vitae by 1st June, 2021. Applications should be sent to: Prof. Sara Checa (

Webinar: Amit Gefen / Synopsys – Computer Models in Wound Care Research

Wed, Jun 23, 2021 6:00 PM – 7:00 PM CEST

COVID-19 has brought the effects of pressure ulcers/injuries and device-related pressure ulcers/injuries in particular, into sharp focus. With the highly increased use of medical devices for the diagnosis and treatment of patients who require intensive care such as continuous positive airway pressure masks or ventilation and feeding tubing, and with the intense use of personal protective equipment e.g. face masks and respirators by healthcare professionals globally, the incidence of device-related tissue damage has risen starkly. This talk will explore the currently known etiology of pressure ulcers/injuries with a focus on the potential risks associated with devices used by patients and health professionals during the current pandemic. The relevant computational bioengineering research underway at the Gefen laboratory at Tel Aviv University will further be discussed.

Presenter: Professor Amit Gefen is currently a Full Professor with the Department of Biomedical Engineering at the Faculty of Engineering of Tel Aviv University and the Berman Chair in Vascular Bioengineering. The research interests of Prof. Gefen are in studying normal and pathological effects of biomechanical factors on the structure and function of cells, tissues and organs, with emphasis on applications in acute and chronic wound research. To date, Prof. Gefen published more than 270 articles in peer-reviewed international journals and multiple edited books on mechanobiology, cell and tissue biomechanics, with applications that are mostly in wound prevention and treatment.

To register click here

Postdoc position at TUEindhoven: Computational and experimental remodeling of heart valves

This vacancy is posted as part of RegMedXB, which stands for “Regenerative Medicine Crossing Borders”. RegMedXB is a virtual institute composed of universities, health foundations, governments and private companies in the Netherlands and Belgium. The partners work together to tackle some of the greatest challenges in regenerative medicine, while building a community of researchers and companies to realize health and economic benefits. The RegMedXB Cardiac Moonshot program aims at developing innovative strategies to regenerate the tissues of the heart, including the myocardium, heart valves and blood vessels.

The current project concentrates on preserving and regenerating heart valve function under non-physiological loading conditions. For this you will investigate the structural and biological remodeling of heart valves using a combination of experimental and computational research.
The experimental research will focus on establishing an ex vivo platform to investigate the remodeling and functionality of heart valves under various hemodynamic conditions.
The computational part focuses on simulating valve remodeling, with the aim of understanding and predicting experimental outcomes, and extrapolating findings to relevant in vivo situations.

If you are fascinated by the engineering aspects of regenerative medicine and eager to develop innovate models and strategies that will advance cardiovascular regeneration, we invite you to join us in this challenge. You will collaborate intensively with our partners in the RegMed-XB Cardiac Moonshot consortium, in particular with the University Medical Centers in Leiden and Utrecht on ex vivo tissue remodeling, and with other TU/e groups on computational modeling and tissue engineering.

More information can be found here:

Joint ESB-VPHi webinar: Imaging of joint tissues

Tue, May 18, 2021 2:00 PM – 3:00 PM CEST

The joint ESB-VPHi webinar takes place on 18 May 2021 featuring Simo Saarakkala from University of Oulu, Finland. Osteoarthritis is the most common joint disease in the world. It can occur in any joint, but it is the most common in hand, knee, hip and spine. Osteoarthritis is a whole joint disease affecting simultaneously several joint tissues, i.e. articular cartilage, subchondral bone, meniscus, synovium, ligaments and tendons. The typical primary signs of osteoarthritis progression are degeneration and wear of articular cartilage along with pathological remodeling of the subchondral bone. During the last decades, we have seen the rapid development of different imaging modalities and digital image analysis methods both at the laboratory level, i.e. tissue and cell level, and at the clinical level. This development has allowed both researchers and clinicians to better understand the initiation and progression of osteoarthritis. Specifically, machine learning based approaches for image analysis have become more common and promising during the recent few years. In this talk, the role of several imaging modalities in osteoarthritis research and clinical diagnostics – along with advanced image analysis methods – will be introduced. From the laboratory imaging methods, we will focus micro-computed tomography (micro-CT), Fourier-transform infrared imaging (FTIRI), Raman microscopic imaging, and polarized light microscopy (PLM). From the clinical imaging methods, we will focus on conventional radiography (X-ray) and the potential of advanced image analysis and deep learning algorithms to mine new diagnostic and prognostic information from them. Finally, the future prospects of clinical prediction models, combining imaging data and clinical information, will be discussed.

To register, click here:

PhD Position in Experimental Micro- and Nanobiomechanics @TUWien

We invite applications for a of a PhD position (University Assistant) in experimental micro- and nanobiomechanics. The position is set within a vibrant research group with a main focus on mechanics of individual collagen fibrils and micromechanics of collagen-rich tissues. The research project to be addressed is two-fold:

1) Conducting scientific research on the mechanics of individual collagen-fibrils as well as micro-mechanics of tissue sections as a function of age, pathology or chemical modification. We have a number of ongoing research projects in this context such that this part will be shaped according to the interests of the applicant.

2) Further development of experimental testing devices for micro- and nanomechanical characterization of individual collagen fibrils and microscopic tissue samples. This is based on a mechanical testing device for nanoscale fibres developed by our team.

Further information and link to apply for this position (deadline April 22nd 2021):

For informal discussion please contact Philipp Thurner (

ESB webinar: Basics of agent-based computer modeling for clinically-related applications

The next ESB webinar, on April 22nd, 2021– 17:00 – 18:00 CEST, is targeted towards individuals interested in agent-based computer modeling approaches to simulate biological processes. In particular, the webinar aims at:

  • Introducing participants to the basics of agent-based modeling
  • Providing examples of their application to investigate clinical-related problems.

By the end of the webinar, attendees will learn the basic principles to build an agent-based model including how to:

  • Simulate individual agents
  • Specify agent properties
  • Define agent behavior and interactions
  • Analyze and visualize model predictions

The webinar will be conducted by Prof. Sara Checa. She is a Junior Professor at the Julius Wolff Institute, Charite-Universitaetsmedizin Berlin, where she leads the research group of “Computational Mechanobiology”. She holds a guest researcher position at the Technical University Berlin as well. She is an expert on computational mechanobiology applied to tissue regeneration and adaptation and has a profound expertise on the development of agent-based computer models to investigate clinical-related questions. She completed her PhD at the University of Southampton and conducted post-doctoral research at the Trinity Center for Bioengineering in Ireland, at Stanford University in the USA and then at the Julius Wolff Institute, where she stayed first as a group leader and now as Professor.

The seminar will last 45 minutes and will be followed by 15 minutes of Q/A from the audience. You will have the chance to ask your questions which will be addressed by the speaker at the end of the webinar. However, it would be great if you could send your question in advance while filling the registration form or by sending to and/or  before the webinar.

Click to register for the webinar.

Please Subscribe to our YouTube channel! (

Looking forward to your attendance.

ESB Student Committee

5th VPH Summer School – June 7-11, online: Tackling Complexity in Health & Medicine

Dear Colleagues,
It is our pleasure to inform you that the 5th VPH Summer School will be held ONLINE, on June 7-11, 2021. This new edition focuses on Tackling Complexity in Health & Medicine. The registration is now open! To register, please click here: link   

The VPH Summer School series is co-organized by the Universitat Pompeu Fabra and by the Virtual Physiological Human Institute (VPHi). It provides junior engineers, early researchers and medical doctors with a complete overview of state-of-the-art Virtual Physiological Human (VPH) research for In Silico Medicine, following a complete pipeline from basic science and clinical needs, to model application. The training includes 15 morning lectures plus one honorary VPH lecture, given by leading international researchers. Speakers details are available here

The key methodological and technological concepts are enriched during the whole week by five afternoon hands-on sessions in multiscale modelling, physiological modelling, computational systems biology and machine learning that stand for 15.5 hours of transversal training in in silico medicine technologies, under the supervision of expert researchers. Hands-on details are available here.

The last afternoon of the VPH Summer School will host a round table co-organized with QUAES, gathering patients, physicians, researchers and public authority representatives to discuss on In silico Medicine and new medical technologies for the society: Awareness, expectations and effective capacity.

Daily scientific discussions and cross-dissemination are further supported by the afternoon poster sessions.   Please join us and share this information among your dissemination channels! 
Best regards,
Jérôme Noailly, on behalf of the Organising Committee.
Full information is available on the webpage

PhD position on the characterization of anticipatory neuromuscular coordination during explosive movements @ University of Poitiers, France

We invite applications for a PhD position at University of Poitiers, France, entitled “Characterization of anticipatory neuromuscular coordination during explosive movements“.

Summary: The objective of this PhD thesis is to characterize anticipatory muscular coordination during iexplosive movements performed by trained female and male athletes. The Ph.D. student will conceive experimental protocols where human participants have to perform explosive dynamic movements. Data will be collected using both human motion analysis (infrared cameras & force sensors) and muscular physiology (electromyography & superfast ultrasound echograph) equipment. Anticipatory neuromuscular coordination recorded during explosive movements will then be analysed using multi-scale and multi-physic models. Joint torques and muscular lengths and activation patterns will be estimated from a personalised musculoskeletal model. Data collected with echographs will help refine the characterization of interactions between muscular and tendinous fibers.

Keywords: Human movement, Biomechanics, Neuromuscular coordination, Motion Analysis, Musculoskeletal Modelling, Experimental studies, Sport.

Supervisors: Dr. Floren COLLOUD & Dr Romain TISSERAND


Applications must be sent by email before April, 20th 2021.

Interview: from May 17th to May 21st 2021.

Project and funding will start October 1st 2021.

Further information:

For informal discussion please contact Floren Colloud (

Associate professor of Mechanobiology @ Mines Saint-Etienne – France

A permanent position of associate professor in mechanobiology is opened at Mines Saint-Etienne (France). Research will be developed at Sainbiose laboratory and will focus on experimental methods to study biological and mechanical evolution of tissues in the osteoarticular or cardiovascular systems.

More information and application at

Application closure is April 23th 2021.