Category Archives: News

General news articles from the ESB.

PhD position on computational modeling of mechanically-driven sprouting angiogenesis @Charité

Background and scope of the work

Angiogenesis, the growth of new blood vessels from pre-existing vessels, constitutes a fundamental physiological process during the regeneration of many tissues, including bone. In a DFG-funded collaborative project, we are using a combined experimental/computational approach to investigate how mechanical forces mediate angiogenesis during bone repair. As part of this project, a PhD position is available to investigate the role of mechanical strains on the growth of new blood vessels using mechano-biological computational models.  

Tasks

You will develop computer models of sprouting angiogenesis taking into account the role played by chemical and mechanical signals in vessel patterning. You will work in close collaboration with project partners working in in vitro and in vivo models to inform and validate the computer models.

Your profile

  • Master Degree in Mechanical Engineering, Computational Biomechanics, Computational Biology or a related discipline
  • Strong programming skills
  • Knowledge of finite element analysis
  • High motivation, curiosity and commitment to scientific excellence
  • Team player skills and enthusiasm to work in a multi-disciplinary, collaborative environment
  • Excellent command in written and spoken English
  • Independent and responsible attitude, collaborative spirit

What we provide

This position is available for a period of three years with the possibility to be extended if new funding is available. You will work in a friendly team and in a unique research environment. As a PhD student, you will be associated to the Berlin-Brandenburg School of Regenerative Therapies (www.bsrt.de) and benefit from the interaction with international scientists.

Starting date: as soon as possible.

Contact:

If you are interested, please send your CV, motivation letter and two references to: Prof. Sara Checa (sara.checa@charite.de)

Virtual Scientific Meeting of the Austrian Chapter of ESB November 30th

A virtual Scientific Meeting of the Austrian Chapter of ESB will take place on Monday, November 30, 2020, 09:30-16:30. 

Please see the agenda for download. 

Please pre-register yourself for the Zoom webinar – see below. After registering, you will automatically receive a confirmation email containing information about joining the meeting.
Please feel free to forward the announcement to any interested colleague.

Practical guidelines: 
* Delegates joining the meeting using the provided link, will have the default capabilities of an „Attendee“, meaning they can observe the meeting content but cannot use their microphone, video or share their screen.

* Delegates are encouraged to submit their questions on-line on the Zoom Q&A at any time during the presentation. After each presentation, the chair will summarize the questions and ask them on behalf of the attendees.

* Attendees are requested to login at the meeting with their full name allowing the organizers to keep track of the participants.

——

You are invited to a Zoom webinar. 
When: Nov 30, 2020 09:30 AM Vienna 
Topic: Scientific meeting of Austrian Chapter of ESB

Register in advance for this webinar:
https://tuwien.zoom.us/webinar/register/WN_3HR2DuWhRsmN7gu9Z_nGLQ


PhD student position at Lund University

We are looking for a PhD student to explore the potential of Neutron scattering for studying soft musculoskeletal tissues and their structural and mechanical changes due to osteoarthritis. The student will be supervised by Prof Hanna Isaksson and Prof Martin Englund and be part of SwedNESS – the Swedish national graduate school for neutron research. 

More information can be found here:
https://lu.varbi.com/en/what:job/jobID:360505/type:job/where:4/apply:1

Post-doc position in the Computational Biomechanics Research Group at University of Glasgow

A one-year postdoc position is available in the Computational Biomechanics Research Group at University of Glasgow. The project is aimed at combining image segmentation with biomechanical calculations and requires experience in scientific code development and nonlinear biomechanics.

For more information on the position, please check https://www.jobs.ac.uk/job/CCF584/research-assistant

and https://my.corehr.com/pls/uogrecruit/erq_jobspec_version_4.jobspec?p_id=044305

More information on my research group can be found at http://userweb.eng.gla.ac.uk/ankush.aggarwal/

and https://www.gla.ac.uk/schools/engineering/staff/ankushaggarwal/

If you have any questions about the position, please email: ankush.aggarwal@glasgow.ac.uk

ESB webinar on ITK-SNAP: Open-Source Software for Medical Image Segmentation

October 27th 2020

15:00 – 16:00 CET

Click here to register for the webinar.

The objective of this webinar is to introduce ITK-SNAP and provide an overview of its capabilities for medical image navigation and segmentation.

In this webinar, attendees will learn some of the core capabilities of ITK-SNAP:

  • Visualization of 3D medical image data
  • Labeling of anatomical structures in 3D images both manually and semi-automatically
  • Loading, editing, and saving segmentation files
  • Rotating and landmarking 3D images
  • Using the ITK-SNAP distributed segmentation service

The webinar will be Led by Dr. Paul Yushkevich (creator of ITK-SNAP) and by Dr. Alison Pouch from the Penn Image Computing and Science Laboratory.

The seminar will last 45 minutes followed by 15 minutes of Q/A from the audience. You will have the chance to ask your questions which will be addressed by the speaker at the end of the webinar. However, it would be great if you could send your question in advance while filling the registration form or by sending to Ehsan.soodmand@charite.de and/or rodrigo.romarowski@grupposandonato.it  before the start of the webinar.

Click here to register for the webinar.

The webinar will be on the GoToWebinar Platform and will be uploaded to our YouTube channel afterwards. The information to join the webinar will be sent to you after your registration.

Please subscribe to our YouTube channel! (https://www.youtube.com/esbiomech )

Looking forward to your attendance.

ESB Student Committee

JMBBM Frontiers Webinar

JMBBM is launching a series of webinars starting from Thursday 15-10-2020. 

They are on various themes, but all around biomedical materials their performance and uses.

The first webinar will take place on Thursday, October 15, at 9 a.m. Boston, 2 p.m. London, 9 p.m. Beijing, and will feature Prof. Viola Vogel, ETH Zurich, with her presentation entitled Unraveling the Secret Language of the Extracellular Matrix.

More info here

https://www.journals.elsevier.com/international-journal-of-mechanical-sciences/news/jmbbm-announces-frontiers-webinar-series

Extended deadline abstracts World TERMIS 2021

Because of high demand, the deadline for submitting abstracts has been extended to 15 September 2020. Do not miss out on this opportunity to submit your abstract!  

Even though we all live in exceptional and uncertain times due to COVID-19, we confirm that the congress will continue to take place in 2021. We are also planning the possibility to give your talk digitally (more information to be announced soon) in case you are not able to travel to the Netherlands. We have all the measures in place to organize the congress in a safe and COVID-19 proof manner and are exploring high quality digital meeting options. If there is any change, we will update this website accordingly.  

Don’t forget to submit your abstract by 15 September 2020 at the latest!  
More information can be found here: https://www.termis.org/WC2021

The congress theme is ‘biologically inspired technology driven regenerative medicine’. Abstracts can be submitted within the following topics:
Cell sources (autologous & allogeneic)
Biomaterial design & development
Biofabrication
Mechanisms of action
Process engineering
Preclinical & Clinical
Enabling technologies: imaging, modelling, fluidics
Regulatory, Business, Consortia, Patients, SYIS, Sister societies  

Postdoc: Computational modeling of kidney toxin transport @Maastricht University

The department of Cell Biology-Inspired Tissue Engineering (cBITE) at the MERLN Institute for Technology-inspired Regenerative Medicine at Maastricht University in the Netherlands invites applications for a post-doctoral position. The post-doctoral researcher will perform cutting-edge research in computational modeling methods applied to regenerative medicine and more specifically, to kidney toxin transport in microfluidic set-ups, organoid culture systems and/or bioartificial kidney devices.

Regenerative medicine holds the promise to cure many of what are now chronic patients, restoring health rather than protracting decline, bettering the lives of millions and at the same time preventing lifelong, expensive care processes: cure instead of care. More specifically, at present, dialysis and transplantation are the only treatment options for end-stage kidney disease. In the Netherlands alone, 6,500 people currently depend on dialysis, approximately 1,300 of which will die this year. Regenerative medicine offers an alternative treatment in the form of a bioengineered kidney. As a first step, the partners of RegMed XB will work towards creating a functional subunit of a bioengineered kidney. This functional subunit is the nephron, of which there are approximately one million in the adult kidney. In order to inform the in vitro experiments as well as design a bioartificial kidney as an intermediate step towards a fully bioengineered kidney, this project will use computational models to simulate toxin transport and calculate the flow and geometry requirements for adequate toxin removal in various set-ups: microfluidic, organoid culture systems and bioartificial devices.

More information can be found at: https://www.academictransfer.com/en/294108/postdoc-computational-modeling-of-kidney-toxin-transport/

11th BSRT symposium: when hypotheses become clinical reality – Berlin 2-4 December 2020

We are delighted to invite you to join us at the upcoming 11th BSRT symposium!  

Regenerative medicine promises to functionally heal tissues and organs previously thought irreparable, by stimulating the body’s own repair mechanisms. But what exactly has been accomplished by this young branch of translational medicine which was only just defined in the 1990s? Are these promises still hypothetical or are they on their way to becoming clinical reality?

In this year’s symposium, experienced scientists and physicians will not only describe their clinical trials, revealing what has been achieved so far in the development of tomorrow’s personalized medicine, but also talking about possibilities for future clinical translation. Speakers will present the latest diagnostic tools used to predict the healing potential of patients, as well as new regenerative therapies to combat various diseases. In addition, they will show how rehabilitation approaches are tailored to the individual needs of the patient. Early-career scientists still ‘at the bench’ doing basic research will also have the opportunity to present their projects and discuss ideas with the potential to reach the clinics. This year, we looked for inspiration from great thinkers of humanity and decided to let ourselves be guided on this journey by quotations from ancient philosophers. They strove in their own ways for enlightenment and truth to further the well-being of humankind, just like we do in the field of regenerative medicine.

Due to the Corona Pandemic, the 11th BSRT symposium will be a face-to-face event for early career scientists with online keynote lectures given by international experts (Hybrid Symposium). However, in the event of another major lockdown in December, we will organise the event as a full online symposium. So, let us learn from the past and look towards the future of regenerative medicine!  

For further information please visit our website at bsrt-symposium.charite.de.

12 PhD positions available in the Disc4All training network

The European community requires early stage researchers (ESRs) who can work across the boundaries of traditional disciplines, integrating experimental and in silico approaches to understand and manage highly prevalent multifactorial disorders, such as musculoskeletal disorders. The Disc4All training network utilises intervertebral disc degeneration (LDD) leading to low back pain (LBP) as a relevant application for the integration of data and computational simulations in translational medicine, to enable rational interpretations of the complexity of the interactions that eventually lead to symptoms.


LBP is the largest cause of morbidity worldwide, yet there remains controversy as to the specific cause leading to poor treatment options and prognosis. LDD is reported to account for 50% of LBP in young adults, but the interplay of factors from genetics, environmental, cellular responses and social and psychological factors is poorly understood. Unfortunately, the integration of such data into a holistic and rational map of degenerative processes and risk factors has not been achieved, requiring creation of professional cross-competencies, which current training programmes in biomedicine, biomedical engineering and translational medicine fail to address, individually.

Disc4All aims to tackle this issue through collaborative expertise of clinicians; computational physicists and biologists; geneticists; computer scientists; cell and molecular biologists; microbiologists; bioinformaticians; and industrial partners. It provides interdisciplinary training in data curation and integration; experimental and theoretical/computational modelling; computer algorithm development; tool generation; and model and simulation platforms to transparently integrate primary data for enhanced clinical interpretations through models and simulations. Complementary training is offered in dissemination; project management; research integrity; ethics; regulation; policy; business strategy; and public and patient engagement. The Disc4All ESRs will provide a new generation of internationally mobile professionals with unique skill sets for the development of thriving careers in translational research applied to multifactorial disorders.

Hiring Institutions:
Hiring Disc4All Members:
• InSilicoTrials (www.insilicotrials.com, See job offer ESR 1)
• Barcelona Supercomputing Center – Centro Nacional de Supercomputación (www.bsc.es – See job offer ESR 2)
• University of Oulu (www.oulu.fi – See job offer ESR 4)
• Galgo Medical (https://www.galgomedical.com – See job offer ESR 5)
• King’s College London (http://www.kcl.ac.uk/aboutkings/index.aspx – See job offer ESR 6)
• Sheffield Hallam University (https://www.shu.ac.uk/research – See job offer ESR 7)
• University of Bern (www.dbmr.unibe.ch – See job offer ESR 9)
• University of Liège (https://www.uliege.be – See job offer ESR 12)


Type of contracts: temporary (36 months)
Job status: full-time
Hours per week: See individual job offers
Offer starting dates: Between November 1st, 2020 and January 31st, 2021
EU Research Framework: H2020 MSCA-ITN-ETN
Marie Curie Grant Agreement Number: 955735

More information: